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Non-Canonical Autophagy: Mechanisms and Pathophysiological Implications

Editat de Giulia Petroni, Lorenzo Galluzzi
en Limba Engleză Paperback – 25 apr 2021
Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between ‘canonical’ and ‘non-canonical’ forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of ‘non-canonical’ autophagy. The book discusses all forms of ‘non-canonical’ autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying ‘non-canonical’ autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies.

  • Presents the most advanced information surrounding the molecular mechanisms underlying non-canonical autophagy
  • Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes
  • Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development
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Specificații

ISBN-13: 9780128205389
ISBN-10: 0128205385
Pagini: 182
Ilustrații: 75 illustrations (25 in full color)
Dimensiuni: 152 x 229 mm
Editura: ELSEVIER SCIENCE

Cuprins

1. Introduction: canonical vs non-canonical autophagy 2. Overview of Canonical Autophagy  3. Overview of Non-Canonical Autophagy 4. LC3-associated phagocytosis (LAP) 5. Autophagy-dependent cell death (ADCD)  6. Therapeutic targeting of non-conventional autophagy: potential benefits and pitfalls  

Recenzii

"This is an excellent book covering molecular mechanisms underlying non-canonical autophagy and the therapeutic potential and development of autophagy modulators. There are very few books which cover the molecular mechanisms underlying non-canonical autophagy. Weighted Numerical Score: 85 - 3 Stars" --© Doody’s Review Service, 2021, Omer Iqbal, reviewer, expert opinion