After the second coming of Christ, the human race is extinct due to a genetic experiment that causes every man, woman and child to mutate into living, breathing, funny looking clowns. Now, 2000 years later, Satano, the devil clown, introduces hard candy, which when ingested by clowns, causes them to get serious. This results in a new development in clown civilization because clowns everywhere are starting to go bad. Sicko, the worst clown gone bad, starts the clown supremacy movement declaring that "All mimes must die " The always hysterical World Circus is converted into the serious Carnival of Despair, where clowns are baptized in liquid Obvious, the most potent hard candy. Things just aren't funny anymore. Meanwhile God and Jesus find themselves in a galactic crisis, which causes them to go to the Greatest Extreme, in search of the All Knowing Owl in the hopes that the Owl can find a solution to their very serious problem. They eventually discover that everything hinges on the planet Earth. But the Earth is in peril as Satano and his minion Sicko are ushering in Armageddon. God, Jesus, Satano, Sicko and the clowns collide in the exciting climax of this great satire.