Obsessive-Compulsive Disorder and Tourette's Syndrome de Steven E. Hyman

Obsessive-Compulsive Disorder and Tourette's Syndrome: The Science of Mental Health

Steven E. Hyman

First published in 2002. Obsessive-compulsive disorder (OCD) and Tourette's syndrome (TS) are treated together in this volume because symptoms of each often co-occur and because there are substantial overlaps in genetic risks and possibly in the neurobiology underlying these disorders.

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OVERVIEW Allen, A. and Hollander, E. 'Body Dysmorphic Disorder.' Psychiatric Clinic of North America 23 (2000). Groopman, J. 'The Doubting Disease: When is Obsession a Sickness?' The New Yorker (April 10, 2000). EPIDEMIOLOGY Horwath, E. and Weissman, M.M. 'The Epidemiology and Cross-National Presentation of Obsessive-Compulsive Disorder.' Psychiatric Clinic of North America 23 (2000). Kadesjo, B. and Gillberg, C. 'Tourette's Disorder: Epidemiology and Comorbidity in Primary School Children.' Journal of the American Academy of Child and Adolescent Psychiatry 39 (2000). GENETICS Pauls, D.L., Raymond, C.L., Stevenson, J.M., and Leckman, J.F. 'A Family Study of Gilles de la Tourette Syndrome.' American Journal of Human Genetics 48 (1991). Nestadt, G., Samuels, J., Riddle, M., Bienvenu, O.J. 3rd, Liang, K.Y., LaBuda, M., Walkup, J., Grados, M., and Hoehn-Saric, R. 'A Family Study of Obsessive-Compulsive Disorder.' Archives of General Psychiatry 57 (2000). NATURAL HISTORY Phillips, K.A., McElroy, S.L., Keck, P.E., Pope, H.G., and Hudson, J.I. 'Body Dysmorphic Disorder: 30 Cases of Imagined Ugliness.' American Journal of Psychiatry 2 (1993). Riddle, M. 'Obsessive-Compulsive Disorder in Children and Adolescents.' British Journal of Psychiatry 35 (1998). Skoog, G. and Skoog, I. 'A 40-Year Follow-Up of Patients with Obsessive-Compulsive Disorder.' Archives of General Psychiatry 56 (1999). NEUROBIOLOGY OF DISEASE Graybiel, A.M., and Rauch, S.L. 'Toward a Neurobiology of Obsessive-Compulsive Disorder.' Neuron 28 (2000). Leckman, J.F., and Riddle, M.A., 'Tourette's Syndrome. When Habit-Forming Systems Form Habits of Their Own?' Neuron 28 (2000). Saxena, S. and Rauch, S.L. 'Functional Neuroimaging and the Neuroanatomy of Obsessive-Compulsive Disorder.' Psychiatric Clinic of North America 23 (2000). Swedo, S.E., Leonard, H.L., Garvey, M., Mittleman, B., Allen, A.J., Perlmutter, S., Lougee, L., Dow, S., Zamkoff, J., and Dubbert, B.K. 'Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections: Clinical Description of the First 50 Cases.' American Journal of Psychiatry 155 (1998). Kurlan, R. 'Tourette's Syndrome and 'PANDAS': Will the Relation Bear Out? Pediatric Autoimmune Neuropsychiatric Disorders Associated with with Streptococcal Infection.' Neurology 50 (1998). Peterson, B.S., Skudlarski, P., Anderson, A.W., Zhang, H., Gatenby, J.C., Lacadie, C.M., Leckman, J.F., and Gore, J.C. 'A Functional Magnetic Resonance Imaging Study of Tic Supression in Tourette's Syndrome.' Archives of General Psychiatry 55 (1998). Szeszko, P.R., Robinson, D., Alvir, J.M., Bilder, R.M., Lencz, T., Ashtari, M., Wu, H., and Bogerts, B. 'Orbital Frontal and Amygdala Volume Reductions in Obsessive-Compulsive Disorder.' Archives of General Ps