Oncology
en Limba Engleză Paperback
There are totally 10 chapters in this book. Chapter 1 shows that chronic IGF-1 stimulation can bypass chemoresistance and support Ewing sarcoma cell apoptosis in combination with the death ligand Apo2L/TRAIL. The findings may have important implications for the biology as well as the clinical management of the Ewing sarcoma family of tumor. Chapter 2 tests total cfDNA concentration, cfDNA integrity, BRAFV600E mutation and RASSF1A promoter methylation associated to cfDNA in melanoma patients and healthy controls in order to identify a sequential multi-marker panel in cfDNA able to increase the predictive capability in the diagnosis of cutaneous melanoma. Chapter 3 overviews transforming growth factor-B (TGF-B)-mediated tumour suppressive pathways and outlines the molecular mechanisms of these effects. Chapter 4 reviews the contribution of urokinase-type plasminogen activator system in breast cancer; the most common cancer in women worldwide. Better understanding of the molecular biology of this malignancy leads to efficient prognosis and therapies for the disease.
Chapter 5 describes how non coding RNA families can influence the development of neuroblastoma and also possibly give further insights to new diagnostic procedures and therapies for this devastating paediatric cancer. Chapter 6 reviews the current knowledge of Thymidine Kinase 1 a clinically relevant cancer biomarker which is significantly elevated in serum and tissue of cancer patients. Measurement of Thymidine Kinase 1 is useful as an aid in diagnosis and prognosis of many different cancer types and has recently been shown to have vast clinical potential especially as a screening and monitoring tool for cancer patients. Chapter 7 discusses the characteristic pathological, immunophenotypic, and genetic features of different GI lymphomas categorized according to World Health Organization (WHO) classification. Chapter 8 provides an overview of the chemokine system in homeostasis and cancer, with a focus on the CX3CL1/CX3CR1 axis to illustrate the complex interplay between the chemokines and other molecules that shape tumor's microenvironment and its progression.
Chapter 9 reviews the recent advances in cohesin and its associate proteins and discusses the relation between their deregulation and tumorigenesis. Cohesin plays a critical role in regulating sister chromatid cohesion and separation, DNA damage signaling and repair, gene expression, as well as centrosome biogenesis, etc. Chapter 10 reviews the current diagnostic issues that are focused on the identification of the thyroid biomarkers. It shows that thyroid biomarkers has a potential to improve the diagnostic accuracy.
Preț: 441.50 lei
Preț vechi: 464.74 lei
-5% Nou
Puncte Express: 662
Preț estimativ în valută:
84.49€ • 87.77$ • 70.18£
84.49€ • 87.77$ • 70.18£
Disponibil
Livrare economică 13-27 ianuarie 25
Preluare comenzi: 021 569.72.76
Specificații
ISBN-13: 9781922227805
ISBN-10: 1922227803
Pagini: 272
Dimensiuni: 203 x 254 x 18 mm
Greutate: 0.54 kg
Editura: Iconcept Press
ISBN-10: 1922227803
Pagini: 272
Dimensiuni: 203 x 254 x 18 mm
Greutate: 0.54 kg
Editura: Iconcept Press