Organic Synthesis in Water

1 Diels-Alder reactions in aqueous media.- 1.1 Introduction.- 1.2 The effect of water on Diels-Alder reactivity.- 1.3 Regioselectivity and endo/exo-selectivity.- 1.4 Diastereofacial selectivity.- 1.5 Synthetic applications.- 1.6 Intramolecular cycloadditions.- References.- 2 Hetero Diels-Alder reactions.- 2.1 Introduction.- 2.2 Aza Diels-Alder reactions in aqueous media.- 2.3 Synthetic exploitation of the aqueous aza Diels-Alder reaction.- 2.4 Retro aza Diels-Alder reactions in aqueous media.- 3.- References.- 3 Claisen rearrangements in aqueous solution.- 3.1 Introduction.- 3.2 Aromatic Claisen rearrangement.- 3.3 Aliphatic Claisen rearrangement.- 3.4 Synthetic exploitation of aqueous Claisen rearrangements.- 3.5 Water as a solvent.- 3.6 Multiparameter correlation-factor analyses.- 3.7 Other developments in Claisen rearrangements in aqueous solution.- 3.8 Summary.- Acknowledgements.- References.- 4 Carbonyl additions and organometallic chemistry in water.- 4.1 Introduction.- 4.2 Barbier-type alkylation reactions.- 4.3 Conjugate 1,4-additions.- 4.4 Cross-aldol and Reformatsky-type reactions.- 4.5 Pinacol coupling reactions.- 4.6 Miscellaneous reactions.- References.- 5 Aqueous transition-metal catalysis.- 5.1 Trends in aqueous transition-metal catalysis.- 5.2 Palladium-catalyzed cross-coupling reactions.- 5.3 Heck reaction.- 5.4 Carbonylation.- 5.5 Hydroformylation.- 5.6 Hydrogenation.- 5.7 Other reactions.- References.- 6 Oxidations and reductions in water.- 6.1 Oxidations in water: introduction.- 6.2 Oxidation of carbon-hydrogen bonds.- 6.3 Oxidation of carbon-carbon double bonds.- 6.4 Other oxidations.- 6.5 Reductions in water: introduction.- 6.6 Reduction of carbon-carbon double and triple bonds.- 6.7 Reduction of carbonyl and nitro functionalities.- 6.8 Other reductions.- References.- 7 Base-catalyzed aldol- and Michael-type condensations in aqueous media.- 7.1 Introduction.- 7.2 Claisen-Schmidt reaction.- 7.3 Vinylogous aldol reaction.- 7.4 Knoevenagel reaction.- 7.5 Tollens reaction.- 7.6 Weiss-Cook reaction.- 7.7 Michael reaction.- References.- 8 Water-stable rare-earth Lewis-add catalysis in aqueous and organic solvents.- 8.1 Introduction.- 8.2 Aldol reactions.- 8.3 Allylation reactions.- 8.4 Diels-Alder reactions.- 8.5 Mannich-type reactions.- 8.6 Imino Diels-Alder reactions: synthesis of pyridine and quinoline derivatives.- 8.7 Asymmetric aza Diels-Alder reactions: synthesis of tetrahydroquinoline derivatives using a chiral lanthanide Lewis acid as catalyst.- 8.8 Micellar systems.- Acknowledgements.- References.