Pokazano, chto ortostaticheskoe snizhenie arterial'nogo davleniya chasto vstrechaetsya u bol'nykh sakharnym diabetom 1 tipa kak proyavlenie diabeticheskoy neyropatii. Ortostaticheskaya gipotenziya assotsiirovana s kognitivnymi narusheniyami. Traditsionno naznachaemye pri arterial'noy gipertenzii i sakharnom diabete ingibitory angiotenzinprvrashchayushchego fermenta sposobny uvelichivat' vyrazhennost' ortosticheskogo snizheniya arterial'nogo davleniya i ne privodyat k korrektsii kognitivnoy disfunktsii. Preparaty metablicheskogo deystviya khotya i neskol'ko umen'shayut kognitivnye narusheniya, ne privodyat k korrektsii ortostaticheskikh narusheniy. Ventoniziruyushchie preparaty v kombinatsii s insulinoterapiey i ingibitorom angiotenzinprevrashchayushchego fermenta ne tolk'o umen'shayut ortostaticheskoe snizhenei arterial'nogo davleniya, no i uluchshayut kognitivnuyu funktsiyu.