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Outcome Measures and Metrics in Systemic Lupus Erythematosus

Editat de Zahi Touma
en Limba Engleză Paperback – 23 iul 2021
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that manifests with a myriad of clinical and laboratory features. The assessment of SLE is comprehensive and includes different core set domains; disease activity, damage, health-related quality of life, adverse events and economic impact. 
This comprehensive book is focused on the instruments and outcome measures utilized in the assessment of SLE. It targets different audiences including physicians, scientists/researchers and different health professionals interested in learning about the art of measurement in SLE. The book highlights the importance of measurement in the assessment of SLE in a clinical settings, research and clinical trials. Each of the chapters provide a systematic approach to the instruments utilized in the assessment of a specific construct in SLE (e.g., disease activity, fatigue, etc.) and incorporate a comprehensive coverage of disease specific and disease generic measures. Italso discusses different patient-reported outcomes that are crucial to reflect patient perceptions of their health condition and cover constructs such as fatigue, pain, anxiety and depression, cognition, frailty, and many others.

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Specificații

ISBN-13: 9783030733025
ISBN-10: 3030733025
Pagini: 642
Ilustrații: XIV, 418 p. 28 illus., 23 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.68 kg
Ediția:1st ed. 2021
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland

Cuprins

1. Introduction: Metrics and Psychometric Properties.- 2. Domains Measured in Systemic Lupus.- 3. Measuring Disease Activity.- 4. Measuring Damage.- 5. Measurements in Lupus Clinical Trials.- 6. Application of Measurements in Clinical Practice.- 7. Patient-reported Outcomes in Lupus.- 8. Health-related Quality of Life in Lupus.- 9. Assessment of Cognitive Function in Lupus.- 10. Assessment of Depression and Anxiety in Lupus.- 11. Assessment of Fatigue and Pain in Lupus.- 12. Emerging Concepts in Lupus: Sleep, Frailty, and Others.- 13. Activities and Participation for Patients with Lupus.

Notă biografică

Zahi Touma, MD, PhD, FACP, FACR
Associate Professor of Medicine, University of Toronto
Clinician-Scientist, Rheumatology, University Health Network and Mount Sinai Hospital
Scientist, Krembil Research Institute
Cross-Appointed Faculty, Institute of Health Policy, Management and Evaluation
Associate Member, Institute of Medical Sciences
Adjunct Scientist, Institute for Work and Health 
Toronto, ON 
Canada


Textul de pe ultima copertă

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that manifests with a myriad of clinical and laboratory features. The assessment of SLE is comprehensive and includes different core set domains; disease activity, damage, health-related quality of life, adverse events and economic impact. 
This comprehensive book is focused on the instruments and outcome measures utilized in the assessment of SLE. It targets different audiences including physicians, scientists/researchers and different health professionals interested in learning about the art of measurement in SLE. The book highlights the importance of measurement in the assessment of SLE in a clinical settings, research and clinical trials. Each of the chapters provide a systematic approach to the instruments utilized in the assessment of a specific construct in SLE (e.g., disease activity, fatigue, etc.) and incorporate a comprehensive coverage of disease specific and disease generic measures. It also discusses different patient-reported outcomes that are crucial to reflect patient perceptions of their health condition and cover constructs such as fatigue, pain, anxiety and depression, cognition, frailty, and many others.

Caracteristici

Highlights the importance of measurement in the assessment of lupus in clinical settings, research, and clinical trials Provides a systematic approach to the metrics utilized in the assessment of disease activity and damage Includes comprehensive coverage of disease-specific and disease-generic metrics of patient-reported outcomes in lupus Discusses the latest modalities in the assessment of cognitive function, anxiety, depression, sleep, and fatigue