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Paclitaxel: Sources, Chemistry, Anticancer Actions, and Current Biotechnology

Editat de Mallappa Kumara Swamy, T. Pullaiah, Zhe-Sheng Chen
en Limba Engleză Paperback – 10 oct 2021
Paclitaxel: Sources, Chemistry, Anticancer Actions, and Current Biotechnology provides a comprehensive survey of Paclitaxel and its derivatives chemistry, biosynthesis and anticancer activities. In addition, biotechnological methods, including cell cultures, the use of bioreactors and metabolic engineering strategies to improve Paclitaxel production are also discussed. The book discusses topics such as mechanisms of action against cancer, novel forms of Paclitaxel for an effective cancer treatment, strategies for enhancing its bioavailability, and the application of nanocarriers for its delivery and chemotherapy of cancer.
This is a valuable resource for cancer researchers, biotechnologists and members of biomedical field who are interested in the promising anticancer qualities of this antineoplastic drug and how to enhance them for better treatments.


  • Presents detailed information about Paclitaxel research, from its discovery to clinical uses and biotechnological routes of commercial production
  • Focuses on Paclitaxel development as an effective chemotherapeutic drug, along with its application in different types of cancers
  • Encompasses descriptive illustrations and workflows to help the reader fully understand the content and easily apply it to their research
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Specificații

ISBN-13: 9780323909518
ISBN-10: 0323909515
Pagini: 354
Ilustrații: 100 illustrations (50 in full color)
Dimensiuni: 191 x 235 x 24 mm
Greutate: 0.73 kg
Editura: ELSEVIER SCIENCE

Cuprins

1. About Cancers and treatment options- An update2. Paclitaxel: Chemistry, synthetic analogues and their anticancer properties3. Taxol: Mechanisms of action against cancer, an update with current research4. Novel forms of Paclitaxel for an effective cancer cure5. Clinical pharmacology of Paclitaxel6. Strategies for enhancing bioavailability of Paclitaxel for cancer treatment7. Application of nanocarriers for Paclitaxel delivery and chemotherapy of cancer8. Paclitaxel: Cancer chemotherapy evidences, advantages, and future directions9. Anticancer Drug Paclitaxel producing plants. Their taxonomy, morphology, identification, distribution and other botanical details (it also includes color photographs of plants)10. Propagation and Micropropagation of Paclitaxel producing plants11. Biotechnology of Paclitaxel producing plants (Paclitaxel production through hairy root cultures, suspension cultures, callus cultures etc)12. Endophytes for the production of anticancer drug, Paclitaxel13. Metabolic engineering strategies to enhance the production of anticancer drug, Paclitaxel14. Paclitaxel and Chemoresistance Chapter15. Overcoming Paclitaxel Resistance16. Paclitaxel and Lung Cancer Treatment17. An update on paclitaxel treatment in Breast cancer-pros and cons