This book primarily discusses the treatment as well as complexities of pancreatitis in a comprehensive manner. Pancreatitis may be chronic or acute. Even though it can be caused by similar etiologies, they tend to follow different natural histories. Nearly 80% of acute pancreatitis (AP) cases are diagnosed to be a result of alcohol misuse and gallstone disease. This disease generally involves the unexpected onset of upper abdominal that is usually serious enough to warrant the patient into seeking immediate medical attention. Majorly, 10-25% cases of this disease are regarded as serious, leading to a related mortality rate of 7-30%. Treatment is conservative and comprises of basic medical support carried out by veteran teams, sometimes in ICUs. Even though most instances of AP are simple and resolve instantly, the presence of complications has considerable prognostic importance. Serious complications like necrosis, hemorrhage, and infection present rates of up to 25%, 50%, and 80% mortality respectively. Other problems like pseudoaneurysm and pseudocyst formation, or venous thrombosis also increase morbidity and mortality to a lesser degree. The occurrence of pancreatic infection must therefore be avoided.