Pathophysiology and Rational Pharmacotherapy of Myocardial Ischemia

1. A Brief History of Angina Pectoris: Change of Concepts and Ideas.- 2. Myocardial Ultrastructure in Ischemia.- 3. Myocardial Metabolism in Ischemia.- 4. Metabolic Imaging of Ischemic Heart Disease by Positron Emission Tomography.- 5. Coagulation, Thrombosis and Fibrinolysis in Myocardial Ischemia.- 6. Regional Myocardial Flow-Function Relationship in Ischemia.- 7. Electrophysiologic and Biochemical Mechanisms Underlying Malignant Ventricular Arrhythmias during Early Myocardial Ischemia.- 8. Reperfused Myocardium: Stunning, Preconditioning, and Reperfusion Injury.- 9. Coronary Vasomotor Tone in Myocardial Ischemia.- 10. Clinical Significance of Coronary Vasomotor Tone in Myocardial Ischemia.- 11. The Challenge of Silent Myocardial Ischemia.- 12. Exercise-Induced Myocardial Ischemia: The Role of Heart Rate Reduction in Therapeutic Approach.- 13. Treatment of Myocardial Ischemia with Beta-Blockers.- 14. Treatment of Myocardial Ischemia with Nitrates.- 15. Treatment of Myocardial Ischemia with Calcium Antagonists.- 16. Combination Anti-Anginal Therapy: Rationale and Results.- 17. Combined Treatment of Stable Effort-Induced Angina and Mixed Angina.