Perinatal Neuropathology
Autor Mirna Lechpammer, Marc Del Bigio, Rebecca Folkerthen Limba Engleză Mixed media product – 15 sep 2021
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Specificații
ISBN-13: 9781107159792
ISBN-10: 1107159792
Pagini: 458
Dimensiuni: 225 x 282 x 25 mm
Greutate: 1.81 kg
Editura: Cambridge University Press
Colecția Cambridge University Press
Locul publicării:New York, United States
ISBN-10: 1107159792
Pagini: 458
Dimensiuni: 225 x 282 x 25 mm
Greutate: 1.81 kg
Editura: Cambridge University Press
Colecția Cambridge University Press
Locul publicării:New York, United States
Cuprins
Part I. Techniques and Practical Considerations: Approach to autopsy of perinatal nervous system: 1. Clinical considerations; 2. Imaging; 3. External exam of fetus/infant; 4. Autopsy and research consent; Ancillary studies: 5. Microbiology; 6. Cytogenetics; 7. Metabolic studies; 8. Toxicology; Prosection techniques: 9. Brain; 10. Spinal cord; 11. Neuromuscular specimens; 12. Eye specimens; Tissue selection: 13. Selection of brain sreas for microscopic examination; 14. Technical considerations in perinatal CNS tissue processing; 15. Staining techniques; Reporting: 16. Formulation of diagnosis; 17. Reporting templates; 18. Medicolegal Considerations; Part II. Human Nervous System Development: Neuroanatomic Site Development: 19. Human nervous system development – embryonic and early fetal events; 20. Cerebral cortex, including germinal matrix; 21. White matter, including myelination; 22. Cerebellum development of rhombic Lip, cerebellar cortex, dentate nucleus; 23. Spinal cord; 24. Skeletal muscle and peripheral nerve; 25. Fetal and infant eye; Growth parameters: Head size and brain weight; Part III. Stillbirth: Autolysis and Artifacts: 27. Autolysis and artefacts; Stillbirths: 28. Stillbirth; Part IV. Disruptions/Hypoxic-Ischemic Injury: Cellular Responses: 29. Neuronal death; 30. Macroglial reactions; 31. Inflammatory responses; Gray matter: 32. Supratentorial grey matter damage and disruptions; 33. Brainstem and spinal cord disruptions; white matter: 34. Periventricular leukomalacia and diffuse white matter injury; Germinal matrix: 35. Periventricular and intraventricular brain hemorrhage ; Cerebellum: 37. Cerebellar lesions; Part V. Malformations: Neural Tube Defects and Patterning Defects: 37. Defects of neural tube Closure and axial mesodermal defects; 38. Disorders of early midline patterning; Hydrocephalus: Fetal and perinatal hydrocephalus; Neuronal migration disorders: 40. Cerebral cortical migration disorders; Genetic syndromes and phacomatoses: 41. Fragile X syndrome; 42. Down syndrome; 43. Edwards's syndrome; 44. Patau syndrome; 45. Tuberous sclerosis complex; 46. Sturge-weber syndrome; 47. Neurocutaneous melanosis; Part VI. Congenital and Perinatal Brain Tumors: 48. Congenital and perinatal brain Tumors; Part VII. Spinal and Neuromuscular Disorders; Arthrogryposis: 49. Arthrogryposis; Spinal muscle atrophy (SMN AND NON-5Q SMA): 50. SMN and non-5q sMA,; Early-Onset hereditary neuropathies: 51. CMT neuropathies; Congenital muscle disorders: 52. Congenital myasthenic syndromes; 53. Congenital muscular dystrophies; 54. Congenital myopathies; 55. Other congenital muscle diseases; Part VIII. Eye Disorders: Congenital Eye Disorders: 56. Congenital eye malformations and Deformations; Part IX. Infections in Utero Infections: Congenital viral, bacterial, and parasitic infections; Peri- and postnatal infections: 58. Meningitis and encephalitis; Part X. Metabolic/Toxic Disorders: Storage diseases: Lysosomal Disorders; 60. Peroxisomal Disorders; Kernicterus: 61. Kernicterus; Mitochondrial diseases: 62.Mitochondrial diseases; Maternal toxin exposure: 63. Ethanol and other agents; Part XI. Forensic Neuropathology: Trauma: 64. Birth trauma; 65. Accidental and non-accidental death; Sudden unexpected death in infancy and childhood: 66. Sudden unexpected death in infancy and childhood.
Notă biografică
Descriere
Provides comprehensive and contemporary guidance on the optimal approach to fetal and infant neuropathology.