This book is an extensive work which shows the relation between the diseases of the oral cavity and its effect on the sytemic health. Periodontal disease is a multifactorial disease and and have been show to have a great influence on the systemic health like the effect of the disease on cardiovascular disease and preterm low birth weight.The presences of periodontal disease modify the condition of systemic health and leads to the several disease process. this work is extensively based on relation of the periodontal disease with cardiovascular disease and preterm low birth weight.