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Pharmacogenetics and Individualized Therapy

Autor Maitland–van de
en Limba Engleză Hardback – 24 mai 2012
The one-stop reference to pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practices Pharmacogenetics and Individualized Therapy offers thorough coverage of the study of the genetic determinants of drug response at the single gene level-and its impact on pharmaceuticals, therapeutics, and clinical practice. Providing an overview of the molecular basis of pharmacogenetics, the book helps readers understand the implications of genetic variability on pharmacokinetics and pharmacodynamics, as well as other aspects such as adverse drug reactions. Providing coverage of specific disease areas, including cardiovascular concerns, cancer and asthma/COPD, transplantation, and pain medication, the book also looks at the clinical practices, along with the psychiatric and ethical issues that have come to dominate conversation about pharmacogenetics. The technological applications of pharmacogenetics, including genotyping, drug disposition (metabolism and enzymes), and the impact of this research on the pharmaceutical industry and regulatory matters are all addressed in chapters by internationally recognized leaders from both academia and industry. Including chapters on specific therapeutic areas and clinical aspects, Pharmacogenetics and Individualized Therapy helps readers, whether they're students or researchers, to understand the implications of genetic variability on pharmacokinetics and pharmacodynamics.
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Specificații

ISBN-13: 9780470433546
ISBN-10: 047043354X
Pagini: 502
Dimensiuni: 157 x 239 x 32 mm
Greutate: 0.84 kg
Editura: Wiley
Locul publicării:Hoboken, United States

Public țintă

Pharmaceutical companies and drug regulatory authorities, researchers (academic and industry) in: pharmaceutical sciences, pharmacology, pharmacy, medicine, genetics, and biomedical sciences

Cuprins


Notă biografică

ANKE-HILSE MAITLAND-van der ZEE, PhD, is Associate Professor of Pharmacogenetics/Pharmacogenomics at Utrecht University, the Netherlands. ANN K. DALY, PhD, is Professor of Pharmacogenetics at Newcastle University, UK.

Descriere

This resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. It opens with the basics of pharmacogenetics, including drug disposition and pharmacodynamics.