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Pheochromocytoma

Autor W.M. Manger, R. W. Jr. Gifford
en Limba Engleză Paperback – 6 noi 2011
This monograph, which was more than five years in preparation, represents a very detailed account of pheochromocytoma, a tumor that is almost invariably lethal if untreated. In addition to its definitive presentation of the subject, this volume contains the most cur­ rent information regarding the diagnosis and management of pheochromocytoma. It is im­ portant to reemphasize the seriousness of diagnosing and treating pheochromocytoma with the aphorism of Esperson and Dahl­ Iversen that although a pheochromocytoma may be morphologically benign it is physio­ logically malignant (280) and with Aranow's characterization of this tumor as a "veritable pharmacological bomb" (20). If managed ap­ propriately by a highly skilled and profes­ sional "bomb squad," this tumor can be re­ moved and the patient cured in at least 90 percent of cases. The secret lies in first sus­ pecting and recognizing the patient who has and then offering the ex­ pheochromocytoma pert management such a patient requires. These facts more than justify this publication, since the internist, pediatrician, obstetrician, ophthalmologist, otolaryngologist, urologist, neurologist, surgeon, anesthesiologist, derma­ tologist, psychiatrist, radiologist, and also the dentist must be made acutely aware of the varied manifestations of this condition and of the pathologic entities which sometimes co- xiv Preface exist with pheochromocytoma. Furthermore, have included a large number of instructive they should have a thorough knowledge of the figures and have emphasized teaching tables.
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Specificații

ISBN-13: 9781461299028
ISBN-10: 1461299020
Pagini: 428
Ilustrații: XXV, 398 p.
Dimensiuni: 210 x 279 x 22 mm
Greutate: 0.96 kg
Ediția:Softcover reprint of the original 1st ed. 1977
Editura: Springer
Colecția Springer
Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

1 Background and Importance.- Magnitude of the Hypertensive Problem.- Incidence of Pheochromocytoma.- Historical.- 2 Catecholamine Metabolism: Biosynthesis, Storage, Release, and Inactivation.- General Remarks.- Sympathetic Nerves.- Chromaffin Cells.- Pheochromocytomas.- 3 Origin, Pathopharmacology, and Pathology.- Nomenclature.- Embryology.- Etiology (Sporadic and Familial).- Age of Occurrence and Sex Predilection.- Location.- Weight and Size.- Physiologic and Pharmacologic Effects.- Gross and Microscopic Appearance.- Ultrastructure.- Malignant Pheochromocytoma.- Pathologic Complications.- 4 Clinical Manifestations.- Frequency and Occurrence of Attacks.- Symptoms.- Signs.- Signs of Complications.- Atypical Manifestations.- Pathologic Entities Sometimes Associated with Pheochromocytoma.- 5 Differential Diagnosis.- General Remarks.- Hypertension.- Anxiety or Psychiatric Disorder.- Hyperthyroidism.- Paroxysmal Tachycardia (Atrial and Nodal).- Hyperdynamic ?-Adrenergic Circulatory State.- Menopause.- Vasodilating Headaches.- Coronary Insufficiency Syndrome.- Acute Hypertensive Encephalopathy.- Diabetes Mellitus.- Renal Parenchymal or Renal Arterial Disease with Hypertension.- Focal Arterial Insufficiency of the Brain.- Intracranial Lesions (With or Without Increased Intracranial Pressure).- Autonomic Hyperreflexia.- Diencephalic Seizure (Autonomic Seizure or Epilepsy; Visceral Seizures) and Syndrome.- Toxemia of Pregnancy (Preeclampsia and Eclampsia).- Hypertensive Crises and Monoamine.- Oxidase Inhibitors.- Carcinoid Tumors.- Hypoglycemia.- Mastocytosis.- Familial Dysautonomia (Riley-Day Syndrome).- Acrodynia (“Pink Disease”).- Neuroblastoma, Ganglioneuroblastoma, and Ganglioneuroma.- Acute Infectious Disease.- Rare Causes of Paroxysmal Hypertension.- FortuitousCircumstances Simulating Pheochromocytoma.- Potential Secondary Diagnoses.- 6 Diagnosis.- General Remarks.- A Guide for Screening.- Pheochromocytoma “Pearls”.- Laboratory Findings.- Electrocardiographic Changes.- Pharmacologic Tests in the Diagnosis of Pheochromocytoma.- Biochemical Tests.- Preoperative Localization of Pheochromocytoma.- 7 Studies on 38 Patients with Pheochromocytoma in Whom Catecholamines Were Determined.- Case Reports.- Blood Pressure and Catecholamine Concentration in Plasma and Tumors of Patients with Pheochromocytoma.- Correlation between Catecholamines in Pheochromocytomas and Elevations of Plasma Catecholamines Due to Actively Secreting Tumors.- Analysis of Findings on 38 Patients with Pheochromocytoma.- Discussion.- 8 Treatment.- Preoperative Evaluation.- Operative Management.- Management of Extraadrenal Pheochromocytomas.- Management of Pheochromocytomas during Pregnancy.- Effect of Anesthesia and Tumor Palpation on Blood Pressure and Plasma Catecholamines.- Operative Mortality and Morbidity.- Recovery Room Observations.- Postoperative Follow-up.- 9 Comments and Conclusions.