The volume presents seventeen studies about the complex interactions between art, media, science, and technology. Zooming in on specific places and historical moments, the authors describe exemplary instances of the fruitful interaction and collaboration between artists, engineers, and scientists. Several analyses of the sites and trajectories of interdisciplinary knowledge production, as well as their ideological and institutional conditions, put a focus on areas such as the early Soviet Union, or the internationally dynamic period of the 1960s and 70s which is covered in essays about collaborative situations in Madrid, Sidney, New York, as well as in Poland, Sweden, and the Canadian West coast. Other essays deal with the work of individuals like Vilém Flusser, Siegfried Giedion, and Jacqueline Tyrwhitt. Beyond the presentation of key moments in the history of art and science collaboration, the volume seeks to raise methodological questions about conceptions of history that take the multiple intersections between academic disciplines and cultural practices into account, and use them for enriching our understanding of creativity, variation, and historical change.Authors: Irina Aristarkhova, Michael Century, Wendy Hui Kyong Chun, Michael Darroch, Kristoffer Gansing, Olga Goriunova, Catherine Hamel, Caroline Seck Langill, Stephen Jones, Ryszard W. Kluszczynski, Janine Marchessault, Laura Marks, Eva Moraga, Nils Röller, Margareta Tillberg, Siegfried Zielinski.