Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions
Editat de Akhileshwar Kumar Srivastava, Mamta Bisht, Ajay Singhen Limba Engleză Paperback – sep 2025
- Considers the therapeutic application of phytochemicals for the treatment of metabolic diseases including cardiovascular disease, obesity, and type 2 diabetes
- Explores phytochemicals at the molecular level, covering signaling pathways of oxidative stress, mitophagy, inflammasomes, molecular chaperones, receptors, and how these mechanisms can be used to treat diseases
- Discusses the use of artificial intelligence and high-throughput omics technologies in plant-based drug discovery
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Specificații
ISBN-13: 9780443316982
ISBN-10: 0443316988
Pagini: 400
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
ISBN-10: 0443316988
Pagini: 400
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
Cuprins
Section 1: Introduction
1. Overview of human metabolic diseases associated with lifestyle
Section 2: Phytochemicals and molecular targets
2. Significance of phytochemicals in metabolic disorders
3. Molecular connection of oxidative stress and metabolic syndrome: Therapeutic role of phytocomponents
4. Epigenetic mechanisms of phytochemicals in cure of metabolic diseases
5. Plant‑derived bioactive peptides for treatment of metabolic disorders
6. Efficiency of phytochemicals to cure metabolic diseases by targeting mitophagy
7. Phytochemicals as promising therapeutic approaches for inflammasome-related metabolic diseases
8. Regulatory impact of phytochemicals on metabolic diseases by targeting Nrf2-ARE signaling mechanism
9. Targeting molecular chaperones with phytochemicals for drug discovery in metabolic ailments
10. Molecular targets of plant nutraceuticals against obesity
11. Molecular insight to cure cardiovascular diseases through plants compounds
12. Mechanistic insights of important medicinal plant compounds in managing type 2 diabetes mellitus
Section 3: Nanotechnology methods
13. Attenuation of hyperlipidemia by medicinal plants with nanotechnological methods
Section 4: Clinical study
14. Clinical evidences of phytochemicals in cure of metabolic diseases
Section 5: Technologies and challenges for plant-based drug discovery
15. Artificial intelligence in plant-based drug discovery against metabolic disorders
16. Integration of high-throughput omics technologies in discovery of phytodrugs to treat metabolic diseases
17. Multi-targets drug design for screening of phytochemicals to cure of metabolic disorders
18. New opportunities and challenges for improving the druggability of plant product against metabolic disorders
1. Overview of human metabolic diseases associated with lifestyle
Section 2: Phytochemicals and molecular targets
2. Significance of phytochemicals in metabolic disorders
3. Molecular connection of oxidative stress and metabolic syndrome: Therapeutic role of phytocomponents
4. Epigenetic mechanisms of phytochemicals in cure of metabolic diseases
5. Plant‑derived bioactive peptides for treatment of metabolic disorders
6. Efficiency of phytochemicals to cure metabolic diseases by targeting mitophagy
7. Phytochemicals as promising therapeutic approaches for inflammasome-related metabolic diseases
8. Regulatory impact of phytochemicals on metabolic diseases by targeting Nrf2-ARE signaling mechanism
9. Targeting molecular chaperones with phytochemicals for drug discovery in metabolic ailments
10. Molecular targets of plant nutraceuticals against obesity
11. Molecular insight to cure cardiovascular diseases through plants compounds
12. Mechanistic insights of important medicinal plant compounds in managing type 2 diabetes mellitus
Section 3: Nanotechnology methods
13. Attenuation of hyperlipidemia by medicinal plants with nanotechnological methods
Section 4: Clinical study
14. Clinical evidences of phytochemicals in cure of metabolic diseases
Section 5: Technologies and challenges for plant-based drug discovery
15. Artificial intelligence in plant-based drug discovery against metabolic disorders
16. Integration of high-throughput omics technologies in discovery of phytodrugs to treat metabolic diseases
17. Multi-targets drug design for screening of phytochemicals to cure of metabolic disorders
18. New opportunities and challenges for improving the druggability of plant product against metabolic disorders