Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications
Editat de Jitender Madan, Ashish Baldi, Monika Chaudhary, Neetu Chopraen Limba Engleză Paperback – 4 iul 2023
The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits.
- Covers mechanism, protocol and therapeutic significance of Polymer-Drug Conjugates
- Outlines updated methods and techniques to enumerate conjugation with related case studies
- Includes comprehensive compilation of marketed and clinical trial drugs conjugated with polymers or linkers
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Specificații
ISBN-13: 9780323916639
ISBN-10: 0323916635
Pagini: 508
Dimensiuni: 152 x 229 x 29 mm
Greutate: 0.83 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 0323916635
Pagini: 508
Dimensiuni: 152 x 229 x 29 mm
Greutate: 0.83 kg
Editura: ELSEVIER SCIENCE
Public țintă
Scientists and organizations working in the field of drug discovery, repurposing and pharmacological interpretationsCuprins
1. Drug Delivery: The conceptual perspectives and therapeutic applications
2. Rational design of linkers in polymer drug conjugates
3. Exploration of polymers in drug delivery: The structural and functional considerations
4. Chemistry of conjugation in drug delivery: The prospects of biodegradable and non-biodegradable bonds
5. Polymer-drug conjugation using ester and orthoester bond: Mechanism, protocols and applications
6. Polymer-drug linking through amide bonds: The chemistry and applications in drug delivery
7. Drug-Polymer conjugate tailoring by disulfide linkage and its exploration in drug distribution
8. Thioether linkage Chemistry: Perspectives and prospects in therapeutic designing
9. Drug targeting to cancer cells through stimuli responsive imine bonds: Fascinating aspects of site specificity
10. Carbamate-drug conjugates in drug delivery: Structural and mechanistic considerations
11. Bonding through phosphodiester moiety: Its implications in pharmaceutical modifications
12. Enzymatically degradable linkers
13. Dendrimer-Drug conjugates
14. Antibody-Drug conjugates
15. Polymer-Drug Conjugates in Clinical Trials: Challenges, Opportunities and Future prospects
2. Rational design of linkers in polymer drug conjugates
3. Exploration of polymers in drug delivery: The structural and functional considerations
4. Chemistry of conjugation in drug delivery: The prospects of biodegradable and non-biodegradable bonds
5. Polymer-drug conjugation using ester and orthoester bond: Mechanism, protocols and applications
6. Polymer-drug linking through amide bonds: The chemistry and applications in drug delivery
7. Drug-Polymer conjugate tailoring by disulfide linkage and its exploration in drug distribution
8. Thioether linkage Chemistry: Perspectives and prospects in therapeutic designing
9. Drug targeting to cancer cells through stimuli responsive imine bonds: Fascinating aspects of site specificity
10. Carbamate-drug conjugates in drug delivery: Structural and mechanistic considerations
11. Bonding through phosphodiester moiety: Its implications in pharmaceutical modifications
12. Enzymatically degradable linkers
13. Dendrimer-Drug conjugates
14. Antibody-Drug conjugates
15. Polymer-Drug Conjugates in Clinical Trials: Challenges, Opportunities and Future prospects