Posttraumatic Epilepsy: Basic and Clinical Aspects
Autor Carrie R. Jonak, Allison R. Peterson, Devin K. Binderen Limba Engleză Paperback – 23 oct 2022
- Reviews the history and epidemiology of posttraumatic epilepsy
- Considers the neuropathology of posttraumatic epilepsy
- Synthesizes studies demonstrating risk factors for susceptibility to epilepsy after head trauma
- Reviews animal models of traumatic brain injury
- Addresses our current understanding of mechanisms of posttraumatic epilepsy
- Explores novel therapeutic approaches to prevent posttraumatic epilepsy
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Specificații
ISBN-13: 9780323900997
ISBN-10: 0323900992
Pagini: 200
Dimensiuni: 152 x 229 x 19 mm
Greutate: 0.34 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 0323900992
Pagini: 200
Dimensiuni: 152 x 229 x 19 mm
Greutate: 0.34 kg
Editura: ELSEVIER SCIENCE
Cuprins
1. History of posttraumatic epilepsy 2. Epidemiology of posttraumatic epilepsy 3. Neuropathology of posttraumatic epilepsy 4. Clinical trials of agents to prevent posttraumatic epilepsy 5. Surgical treatment of posttraumatic epilepsy 6. Animal models of traumatic brain injury 7. Incidence of posttraumatic epilepsy in animal models of traumatic brain injury 8. Cellular and molecular changes in animal models of posttraumatic epilepsy 9. Blood-brain barrier disruption and posttraumatic epilepsy 10. Inflammation and posttraumatic epilepsy 11. Biomarkers and treatment trials in animal models to prevent posttraumatic epilepsy 12. Therapeutic targets and future directions
Recenzii
"With this comprehensive summary of the important animal model studies to date, the authors demonstrate that continued PTE research in humans is essential. It is crucial to know how to optimize PTE animal models and conduct detailed electrophysiological, cellular, and molecular analyses of PTE versus non-PTE brains in humans. Such future studies will help to identify more selective and precise therapies to treat PTE. We congratulate the authors for presenting this most comprehensive review of PTE from both basic science and clinical perspectives." --Journal of Neurosurgery