Jack the Ripper, sadistic madman of old London, once thought long dead, has returned to New York in an effort to quench his thirst for blood and mayhem. When the city's vampire enclave finds itself insufficient to deal with a madman of Jack's caliber, Vincent, the enclave head, enlists Leo Malone to put the maniac down before he reveals the existence of vampires as he throws the city into the throws of chaos and terror. Leo soon finds that Jack is not the only monster with which he must contend. A ghost from his past has also seemingly crawled from its grave and seeks to put an end to him and the rest of his kind.