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Principles of Biochemistry: International Edition de Robert Horton

Principles of Biochemistry: International Edition

Autor Robert Horton, Laurence A. Moran, Gray Scrimgeour, Marc Perry, David Rawn
en Limba Engleză Paperback – 30 iun 2005
For one-semester or two-semester introductory courses in Biochemistry. May be taught out of departments of chemistry, biology, or biochemistry. Biochemistry departments may be in faculties of science or in medicine.
This concise, introductory text focuses on the basic principles of biochemistry, filling the gap between the encyclopedic volumes and the cursory overview texts. The book has a well-deserved reputation for being the most accurate biochemistry textbook in the market. Widely praised in its previous edition for currency, and clarity of exposition, the new edition has been thoroughly revised and updated to reflect recent changes in this dynamic discipline.

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Specificații

ISBN-13: 9780131977365
ISBN-10: 0131977369
Pagini: 896
Dimensiuni: 216 x 276 mm
Greutate: 1.8 kg
Ediția:4Nouă
Editura: Pearson Education
Colecția Pearson Education
Locul publicării:Upper Saddle River, United States

Cuprins

 
Chapter 1 Introduction to Biochemistry
 
Chapter 2  Water
 
 
Part Two Structure and Function
 
Chapter 3 Amino Acids and the Primary Structures of Proteins
 
Chapter 4 Proteins: Three-Dimensional Structure and Function
 
Chapter 5 Properties of Enzymes
 
Chapter 6 Mechanisms of Enzymes
 
Chapter 7 Coenzymes and Vitamins
 
Chapter 8 Carbohydrates
 
Chapter 9 Lipids and Membranes
 
 
 
PART THREE Metabolism and Bioenergetics
 
Chapter 10 Introduction to Metabolism
 
Chapter 11 Glycolysis
 
Chapter 12 Gluconeogenesis, The Pentose Phosphate Pathway, and Glycogen Metabolism
 
Chapter 13 The Citric Acid Cycle
 
Chapter 14 Electron Transport and ATP Synthesis
  
Chapter 15 Photosynthesis
 
Chapter 16 Lipid Metabolism
 
Chapter 17 Amino Acid Metabolism
  
Chapter 18 Nucleotide Metabolism
 
 
Part Four Biological Information Flow
 
Chapter 19 Nucleic Acids
  
Chapter 20 DNA Replication, Repair, and Recombination
 
Chapter 21 Transcription and RNA Processing
 
Chapter 22 Protein Synthesis
 
Chapter 23 Recombinant DNA Technology
 
  Solutions
 
Illustrations and Credits
 
Glossary
 
Index

Caracteristici

  •  Unique focus on principles and underlying themes of biochemistry.
    • Fosters understanding rather than simply relating facts, establishing a framework of key principles which are then reinforced with the careful use of illustrative examples. Also, encourages understanding over memorization. (Ex. Chapter 6: Mechanisms of Enzymes.)
  • Balanced coverage of biomolecular structure/function, metabolism, and molecular biology. Includes a chapter on photosynthesis.
    • Provides instructors with thorough, consistent coverage of all the topics they cover in class. Emphasis on the relationship between structure and function.  Material in the later chapters builds on principles in the first part of the book. (Ex. Chapter 20: Transcription and RNA Processing.)
  • Strong chemical focus–Including mechanisms of reactions and attention to the physical chemistry of biomolecules.
    • Explains how and why reactions happen so students can understand more and memorize less. (Ex. Chapter 7: Coenzymes.)
 
  • New emphasis on oxidation-reduction reactions.
Expands coverage of these important reactions and explains electron gain and loss in a simple and straightforward manner. Principles and concepts are covered in a revised chapter on metabolic strategies. Electron transport and photosynthesis chapters have been extensively revised.
 
  • Evolutionary Approach to biochemistry.
The fundamental strategies of metabolic pathways are explained from the perspective of how they evolved. 
The fourth edition places more emphasis on biosynthesis pathways since they are of fundamental importance for most species. Catabolic pathways are usually described after the synthesis of particular biomolecules has been explained.  (Exception: glycolysis.) This extends a trend that has been developing in all biochemistry textbooks over the past decade.  
  • Authoritatively written by a collaborative team of experts.
    • Provides students with clear, lucid explanations and accurate science for all areas of biochemistry. (Ex. DNA replication.)
  • Chapters on amino acid, lipid, and nucleotide metabolism stress core concepts.
    • Students leaves this short course with a good understanding of the key issues of metabolism and don't lose sight of the forest for the trees.
  • NEW - Completely updated to reflect the latest understanding and discoveries in biochemistry–Maintains the standard of currency and accuracy set by the previous edition.
    • Provides the most up-to-date coverage of the material. Ex. Electron transport.
    • Incorporates information from genome sequencing projects in order to understand which metabolic pathways are present in an organism and which enzymes are used. (Ex. Citric acid cycle, Lipid metabolism.)
  • Excellent coverage of gene expression–Including the structure of RNA polymerase, the structure of the ribosome, genome organization, repair mechanisms, regulation of transcription and translation, and the structure and evolution of aminoacyl tRNA synthetases.
    • Offers the most up-to-date treatment of molecular biology available in this rapidly changing area. (Ex. Ribosome structure.)
  • NEW - Many new protein structures.
    • Reflecting recent developments in technology and understanding, the book helps students appreciate the intricacies and dynamics of macromolecular structure.
  • NEW - Boxes focus on interesting science, commercial  applications of biochemistry, and medical relevance.
    • New boxes on enzyme evolution, enzyme microheterogeneity, sources of electrons in redox reactions, and the origins of common names help stimulate student’s interest in the science of biochemistry.
    • New boxes on genetically modified foods and improving crop production illustrate some of the commercial applications of biochemistry.
    • New boxes on ABO blood groups, statins, and common painkillers illustrate principles described in the text using clinical examples.

Caracteristici noi

  • Completely updated to reflect the latest understanding and discoveries in biochemistry–Maintains the standard of currency and accuracy set by the previous edition.
  • New developments in the area of gene expression–Including the structure of RNA polymerase, the structure of the ribosome, genome organization, repair mechanisms, regulation of transcription and translation, and the structure and evolution of aminoacyl tRNA synthetases.
  • Many new protein structures.
    • Reflecting recent developments in technology and understanding, the book helps students appreciate the intricacies and dynamics of macromolecular structure.  The latest thinking on protein folding and chaperones is explained concisely and accurately.
    • Newly published structures of complex III and bacterial photosystems are illustrated and described. Reactions such as the Q cycle are now presented as part of a structure-function theme.
  • New emphasis on how pathways evolved.
  • More emphasis on redox reactions.
  • Application Boxes focus on applications of biochemistry (clinical, agricultural, industrial, and commercial).
  • Enhanced art program takes advantage of new rendering technologies to make more illustrative figures.
  • Revised CW site–Includes hundreds of traditional and clinical computer-graded questions, biomolecular models, and links to relevant sites like enzyme and metabolism databases.
    • Enables students to practice, visualize 3-D models, and find supplementary information. Ex.___
  • New Media Labs Online–Feature online research and study exercises, harnessing the power of the Internet in this dynamic discipline. Perfect for instructors to assign as group exercises.