Principles of Developmental Genetics
Editat de Sally A. Moodyen Limba Engleză Hardback – 11 sep 2014
- All-new coverage of systems biology and stem cell biology in context of evolving technologies places the work squarely on the modern sciences
- Chapters are complemented with a bulleted summary for easy digestion of the major points, with a clinical summary for therapeutic application
- Clinical highlights provides a bridge between basic developmental biology and clinical sciences in embryonic and prenatal syndromes
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Specificații
ISBN-13: 9780124059450
ISBN-10: 0124059457
Pagini: 784
Dimensiuni: 216 x 276 x 41 mm
Greutate: 2.31 kg
Ediția:Revised
Editura: ELSEVIER SCIENCE
ISBN-10: 0124059457
Pagini: 784
Dimensiuni: 216 x 276 x 41 mm
Greutate: 2.31 kg
Ediția:Revised
Editura: ELSEVIER SCIENCE
Cuprins
Section I: Emerging Technologies and Systems Biology 1. Untangling the Gordian knot: Cell signaling events that instruct development 2. RNA-seq and deep sequencing 3. Using mutagenesis in mice and zebrafish for developmental gene discovery 4. Chemical approaches to control stem cell fate 5. BMP signaling and stem cell self-renewal in the Drosophila ovary 6. Genomic Analyses of Neural Stem Cells 7. Chordate origins, stem cells and regeneration
Section II: Early Embryology and Morphogenesis 8. Dorsal-ventral axis patterning in insects 9. Building dimorphic forms: an examination of the genetic pathways that intersect embryonic patterning and sex determination 10. Anterior-Posterior patterning in mammals 11. Early development of epidermis and neural tissue 12. Taking the middle road: mesoderm induction and the blastula-gastrula transition 13. Endoderm induction 14. Epithelial branching: mechanisms of patterning and self-organization 15. Lateral line migration
Section III: Organogenesis 16. Neural cell fate determination 17. Retinal development 18. Neural crest determination 19. Determination of preplacodal ectoderm and sensory placodes 20. Olfactory development 21. Inner ear development 22. Molecular genetics of tooth development 23. Induction of the cardiac lineages 24. Blood vessel formation 25. Blood induction and embryonic formation 26. Vertebrate kidney formation: a comparative perspective 27. Development of the genital system 28. Skeletal development 29. Formation of vertebrate limbs 30. Patterning the embryonic endoderm into presumptive organ domains 31. Pancreas Development and Regeneration
Section IV: Selected Clinical Problems 32. Diaphragmatic embryogenesis and human congenital diaphragmatic defects 33. Genetic and developmental basis of congenital cardiovascular malformations 34. Multiple Roles of T-box genes 35. Craniofacial syndromes: etiology, impact and treatment 36. DeGeorge and related syndromes 37. Neural tube defects
Section II: Early Embryology and Morphogenesis 8. Dorsal-ventral axis patterning in insects 9. Building dimorphic forms: an examination of the genetic pathways that intersect embryonic patterning and sex determination 10. Anterior-Posterior patterning in mammals 11. Early development of epidermis and neural tissue 12. Taking the middle road: mesoderm induction and the blastula-gastrula transition 13. Endoderm induction 14. Epithelial branching: mechanisms of patterning and self-organization 15. Lateral line migration
Section III: Organogenesis 16. Neural cell fate determination 17. Retinal development 18. Neural crest determination 19. Determination of preplacodal ectoderm and sensory placodes 20. Olfactory development 21. Inner ear development 22. Molecular genetics of tooth development 23. Induction of the cardiac lineages 24. Blood vessel formation 25. Blood induction and embryonic formation 26. Vertebrate kidney formation: a comparative perspective 27. Development of the genital system 28. Skeletal development 29. Formation of vertebrate limbs 30. Patterning the embryonic endoderm into presumptive organ domains 31. Pancreas Development and Regeneration
Section IV: Selected Clinical Problems 32. Diaphragmatic embryogenesis and human congenital diaphragmatic defects 33. Genetic and developmental basis of congenital cardiovascular malformations 34. Multiple Roles of T-box genes 35. Craniofacial syndromes: etiology, impact and treatment 36. DeGeorge and related syndromes 37. Neural tube defects
Recenzii
"...expert coverage of all major events in early embryogenesis and the organogenesis of specific systems, supplemented with representative clinical syndromes." --Anticancer Research