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Prions and Mad Cow Disease de Brian K. Nunnally

Prions and Mad Cow Disease

Editat de Brian K. Nunnally, Ira S. Krull
en Limba Engleză Hardback – 17 oct 2003
The alarm sounded by Canada's recently confirmed case of bovine spongiform encephalopathy (BSE) has reaffirmed the exigency of establishing improved safeguards and more aggressive surveillance protocols in North America and around the world. Research converging on the probable causative agent-prion proteins-calls for intensive assessment of the headway gained in tracing prions, testing for transmissible neurodegenerative diseases, and developing methods for cornering the epidemic. Administered by an illustrious panel of 36 international contributors, this timely book marshals techniques for prion protein assay and diagnosis of transmissible spongiform encephalopathies (TSEs).
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Specificații

ISBN-13: 9780824740832
ISBN-10: 0824740831
Pagini: 452
Dimensiuni: 152 x 229 x 26 mm
Greutate: 0.73 kg
Ediția:New.
Editura: CRC Press
Colecția CRC Press

Public țintă

Professional

Cuprins

Foreword, Preface, Contributors, 1. Taking Aim at the Transmissible Spongiform Encephalopathies Infectious Agents, 2. Prions, the Protein Hypothesis, and Scientific Revolutions, 3. A Simulation Model for Evaluating the Potential for Spread of Bovine Spongiform Encephalopathy in Animals or to People, 4. Actions to Prevent Bovine Spongiform Encephalopathy from Entering the United States, 5. Overview of Transmissible Spongiform Encephalopathy in Cervids in the United States, 6. Bioassays for Prions, 7. Cyclic Amplification of Scrapie Prion Protein: Implications for Diagnosis, 8. The Enfer Transmissible Spongiform Encephalopathies Assay: Chemiluminescent ELISA of Prion Proteins, 9. Sensitive Detection of Prion Proteins by Immunoassay: CEA/Bio-Rad Test, 10. The Diagnosis of Transmissible Spongiform Encephalopathies Using Differential Extraction and DELFIA, 11. In Vivo Diagnosis of Prion Diseases, 12. Diagnosis of Prion Diseases by Multispectral Techniques, 13. Detection of the Prion Protein in Blood Using a Fluorescence Immunoassay, 14. Prion Detection and Application to the Safety of Biological Products, Index

Notă biografică

Brian K. Nunnally and Ira S. Krull

Descriere

The alarm sounded by Canada's confirmed case of bovine spongiform encephalopathy (BSE) has reaffirmed the exigency of establishing improved safeguards and more aggressive surveillance protocols in North America and around the world. Research converging on the probable causative agent--prion proteins--calls for intensive assessment of the headway gained in tracing prions, testing for transmissible neurodegenerative diseases, and developing methods for cornering the epidemic. With an illustrious panel of 36 international contributors, this timely book marshals techniques for prion protein assay and diagnosis of transmissible spongiform encephalopathies (TSEs).