Proceedings of the Twenty-Fifth Symposium on Biotechnology for Fuels and Chemicals Held May 4–7, 2003, in Breckenridge, CO: ABAB Symposium

1 Molecular Diagnostics in Neoplastic Hematopathology Daniel A. Arber 2 HER2 and Topoisomerase IIa in Breast Carcinoma Kenneth J. Bloom 3 Study of Sentinel Lymph Nodes for Staging Malignant Neoplasms Alice A. Roberts and Alistair J. Cochran 4 Prostate Cancer Markers: From Discovery to the Clinic Judith A. Finlay, Stephen D. Mikolajczyk, Thomas M. Pribyl, R. Bruce Wallace, and Harry G. Rittenhouse 5 Diagnosis of Ataxia-Telangiectasia: ATM Mutations Associated with Cancer Midori Mitui, Shareef A. Nahas, Helen H. Chun, and Richard A. Gatti 6 Microsatellite Alterations as Diagnostic and Prognostic Markers in Patients with Cancer Bret Taback and Dave S. B. Hoon 7 Chromosomal and Molecular Cytogenetic Assays for Evaluation of Human Tumors Peter C. Hu, Armand B. Glassman, and Vicki L. Hopwood 8 New Insights and Future Advances in Cancer Diagnostics: Limitations of Conventional Tumor Markers Yasushi Kasahara and Yutaka Tsukada 9 MHC Tetramers: A Tool for Direct Ex Vivo Detection and Enumeration of Tumor Specific Cytotoxic T Cells Kristine Kuus-Reichel, Jennie Chang, Ferdynand Kos, and Charles T. Nugent 10 Serum Tumor Marker Test Profile in Testicular Germ Cell Tumors Frank J. Liu, Robert M. Nakamura, C. Howard Tseng, and Kevin S. Liu 11 A Marker for Early Diagnosis of Lung Cancer: The Heterogeneous Nuclear Ribonucleoprotein A2/B1 (hnRNP A2/B1) Jordi Tauler, Alfredo Martinez, and James L. Mulshine 12 New Applications of Flow Cytometry in Cancer Diagnosis and Therapy Sophie Song and Faramarz Naeim 13 The Changing Role of the Pathologist in the Management of the Cancer Patient Raymond B. Nagle 14 General Considerations in the Use and Application of Laboratory Tests for the Evaluation of Cancer Robert M. Nakamura and WayneW. Grody 15 Autoantibodies, Autoimmunity, and Cancers: Markers for Identification of Early Stages of Tumors Robert M. Nakamura and Eng M. Tan 16 Molecular Techniques in Cancer Diagnosis and Management Jeffrey S. Ross, Karen Gray, Rebecca Mosher, and James Stec 17 DNA Repair Defects in Cancer Ramune Reliene and Robert H. Schiestl 18 Genetic Counseling for Hereditary Cancer Predisposition Testing Joyce L. Seldon and Patricia A. Ganz 19 Types of Circulating Tumor Markers and Their Clinical Applications James T. Wu 20 Identification of Risk Factors for Early Neoplasm James T. Wu 21 Emerging Circulating Tumor Markers James T. Wu 22 Recent Advances in Molecular Classification and Prognosis of Colorectal Cancer Tsung-Teh Wu and Asif Rashid

In Biotechnology for Fuels and Chemicals: The Twenty-Fifth Symposium, leading American and international researchers from academia, industry, and government present the latest research and breakthroughs on how biotechnology is being used to produce economically competitive fuels and chemicals in a sustainable and environmentally responsible manner. The contributors discuss both fundamental science discoveries and the progress that has been made in commercialization efforts. Special attention is given to biofeedstock (plant genomics, production, and pretreatment), bioprocessing, direct production in plants, and the use of molecular biology and genomics to create new biocatalysts. The field continues to expand, and the ideas and techniques described here will play important roles in developing new biological processes for producing fuels and chemicals on a large scale, as well as for reducing pollution and waste disposal problems and their adverse impacts on global climate change. Cutting-edge and authoritative, Biotechnology for Fuels and Chemicals: The Twenty-Fifth Symposium provides an excellent overview of current research and development in the production of commodity fuels and chemicals via biological transformation.