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Progress in Drug Research: Progress in Drug Research, cartea 55

Contribuţii de Q.May Wang, Beverly A. Heinz, Jay A. Glasel, Gerlie C.de los Reyes, Robert T. Koda, Eric J. Lien, Angelo Vedani, Max Dobler, Paul A. Keifer, Laurane G. Mendelsohn, Satya P. Gupta
en Limba Engleză Paperback – 30 oct 2012
Hepatitis C virus (HCV) was first identified in 1989 as the etiologic agent of non-A, non-B hepatitis [1] and is currently recognized as the leading cause of chronic liver disease worldwide. In contrast to hepatitis B virus infection, in which only about 5% of adult infections become chronic, more than 80% of HCV-infected patients develop chronic hepatitis. Moreover, 20-50% of those persistently infected with HCV will develop liver cirrhosis and hepatocellu­ lar carcinoma (HCC) [2]. It is estimated that there are 10,000 deaths in the USA per year due to chronic liver failure or HCC [3]. In addition, HCV dis­ 25-50% of all liver transplants in US centers, and the ease is responsible for recurrence of HCV infection following liver transplantation is universal [4]. Typically, HCV disease emerges after a 10-20 year period during which symp­ toms, if they exist at all, are mild and non-specific. Although the prevalence varies greatly among different countries, it has been estimated that up to 170 million people (3% of the world's population), are infected with HCV [5]. A recent study in the USA found that 65% of all HCV-infected persons are 30 to 49 years old [6].
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Specificații

ISBN-13: 9783034895446
ISBN-10: 3034895445
Pagini: 348
Ilustrații: VIII, 336 p.
Dimensiuni: 178 x 254 x 18 mm
Greutate: 0.6 kg
Ediția:Softcover reprint of the original 1st ed. 2000
Editura: Birkhäuser Basel
Colecția Birkhäuser
Seria Progress in Drug Research

Locul publicării:Basel, Switzerland

Public țintă

Research

Cuprins

Recent advances in prevention and treatment of hepatitis C virus infections.- The effects of morphine on cell proliferation.- Glucosamine and chondroitin sulfates in the treatment of osteoarthritis: a survey.- Multi-dimensional QSAR in drug research.- NMR spectroscopy in drug discovery: Tools for combinatorial chemistry, natural products, and metabolism research.- Prostate cancer and the androgen receptor: Strategies for the development of novel therapeutics.- Quantitative structure-activity relationships of cardiotonic agents.- Index Vol. 55.- Index of titles, Vol. 1-55.- Author and paper index, Vol. 1-55.

Caracteristici

WELL-ESTABLISHED BOOK SERIES CONTAINING REVIEWS ON A WIDE SPECTRUM OF HIGHLY TOPICAL AREAS IN CURRENT PHARMACEUTICAL AND PHARMACOLOGICAL RESEARCH