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Progress in Virus Research

Editat de Sabine Thebault
en Limba Engleză Hardback – 5 iun 2005
The first part of the book deals with several aspects of different viruses : viral structure, function, replication and interplay between the virus and the host. Six viruses are used as examples, four RNA viruses (HTLV-I, HIV-1, MMTV and coxsackievirus B4) and two DNA viruses (EBV and KSHV). The second part of the book is devoted to the use of the knowledge on viruses to practical applications and also to the characterisation of HIV inhibitors. Reviewing the results of research on different viruses is important since, although viruses possess vast degrees of complexity, they also share similar features. In addition, viruses are more and more used as models to solve molecular biology problems.
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Specificații

ISBN-13: 9781594544385
ISBN-10: 1594544387
Pagini: 336
Ilustrații: tables & charts
Dimensiuni: 187 x 263 x 29 mm
Greutate: 0.95 kg
Editura: Nova Science Publishers Inc

Cuprins

Preface: Regulation of viral and cellular transcription by the human T-cell leukaemia virus type I tax oncoprotein; De-regulation of the cell cycle by human T-cell leukaemia virus type I (HTLV-I) tax: Mechanisms and effects; Advances in understanding the roles of the cell in HIV-1 assembly; The interactions of immunodeficiency viruses with antigen presenting cells; Mechanisms of retrovirus-host interaction revealed through studies of mouse genetic models; Coxsackievirus B4 and type 1 diabetes; EBV associated malignancies: Epidemiology, pathogenesis and therapeutic perspectives; Developments in understanding the mechanism of tumorigenesis mediated by Kaposi's sarcoma associated herpesvirus; Retroviral insertional mutagenesis and its application to genetically engineered mice; Insights into integration site selection: Application for vector design; Entry inhibitors, the emerging family of anti-HIV drugs.