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Protein Oxidation and Aging: Wiley Series in Protein and Peptide Science

Autor T Grune
en Limba Engleză Hardback – 31 ian 2013
Reviews our current understanding of the role of protein oxidation in aging and age-related diseases Protein oxidation is at the core of the aging process. Setting forth a variety of new methods and approaches, this book helps researchers conveniently by exploring the aging process and developing more effective therapies to prevent or treat age-related diseases. There have been many studies dedicated to the relationship between protein oxidation and age-related pathology; now it is possible for researchers and readers to learn new techniques as utilizing protein oxidation products as biomarkers for aging. Protein Oxidation and Aging begins with a description of the tremendous variety of protein oxidation products. Furthermore, it covers: * Major aspects of the protein oxidation process * Cellular mechanisms for managing oxidized proteins * Role of protein oxidation in aging * Influence of genetic and environmental factors on protein oxidation * Measuring protein oxidation in the aging process * Protein oxidation in age-related diseases References at the end of each chapter serve as a gateway to the growing body of original research studies and reviews in the field.
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Specificații

ISBN-13: 9780470878286
ISBN-10: 0470878282
Pagini: 516
Dimensiuni: 164 x 241 x 32 mm
Greutate: 0.86 kg
Editura: Wiley
Seria Wiley Series in Protein and Peptide Science

Locul publicării:Hoboken, United States

Public țintă

Biochemists, nutritionists, cell and molecular biologists, medical researchers; researchers working in aging, molecular medicine, pharmacology and drug discovery, nutraceutical scientists, oncology researchers.  

Cuprins


Notă biografică

TILMAN GRUNE, MD, is Full Professor and Director of the Institute of Nutrition at Friedrich Schiller University Jena. His research examines the biological phenomenon of oxidative stress. In particular, his research group has been investigating the oxidative stress response of cells and organisms and the protective influence of antioxidants. BETUL CATALGOL, MD, is Assistant Professor in the Faculty of Medicine and the Department of Biochemistry at Marmara University. She is coauthor of Proteasome and Neurodegenerative Diseases, Proteasome and Cancer, and Protein Carbonyl Measurement by Enzyme-Linked Immunosorbent Assay. TOBIAS JUNG, PhD, is a Research Assistant at Friedrich Schiller University Jena. He is coauthor of Structure of the Proteasome.

Descriere

As the lifespan of humans increases, research into aging and its related pathological conditions is gaining momentum. This book is the first to explain protein oxidation and the aging process, focusing on the connection between protein disturbances and the oxidative stress that cells continually undergo.