The setting is the fictional Missouri frontier town of Dawson's Landing on the banks of the Mississippi River in the first half of the 19th century. David Wilson, a young lawyer, moves to town and a clever remark of his is misunderstood, which causes locals to brand him a "pudd'nhead" - a nitwit. His hobby of collecting fingerprints does not raise his standing in the townsfolk's eyes, who see him as an eccentric and do not frequent his law practice.