This book is a compendium from national and international thought leaders in health care quality. The aim is to provide readers with diverse and leading views in the burgeoning field of quality, safety, and value. We do not intend to repeat or replace the seminal efforts of Avedis Donabedian and other pioneers in health care quality. Rather, the intent is to compliment the rich journey of continuous improvement in health care with a current, state-of-the-art view. The chapters in this book may be read in any order and asynchronously without compromising the value of the experience and education. Finally, we aim to stimulate further thought and action to help our patients and health care institutions in the quest to provide high-performance and high-reliability health care on top of a foundation of rapid, institutional learning.