Predstavleny rezul'taty izucheniya strukturno-funktsional'nogo sostoyaniya pula rastvorimykh differentsirovochnykh molekul i molekul gistosovmestimosti pri takikh onkologicheskikh zabolevaniyakh kak rak tela matki, rak legkogo, mioma matki, khronicheskiy mieloleykoz, ostrye leykozy, melanoma. Issledovano syvorotochnoe soderzhanie summarnykh fraktsiy rastvorimykh differentsirovochnykh molekul SD8, CD18, CD25, CD38, CD50, CD54, CD95, molekul gistosovmestimosti HLA I i II klassov, oligomernykh fraktsiy molekul SD8, CD25, CD38, CD50, CD54, CD95, izmeneniy kontsentratsiy rastvorimykh assotsiatov molekul CD18 i CD54 (CD18-CD54), molekul CD18 i CD54 (CD18-CD50), molekul HLA I klassa i CD8 (HLA-I-CD8). Pokazan shirokiy spektr izmeneniy syvorotochnogo urovnya rastvorimykh differentsirovochnykh molekul i molekul glavnogo kompleksa gistosovmestimosti, otrazhayushchiy osobennosti immunnogo otveta, kharakter razvitiya zabolevaniya, monitoringovuyu i differentsial'no-diagnosticheskuyu znachimost' rastvorimykh differentsirovochnykh molekul pri onkozabolevaniyakh raznogo geneza.