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Recent Advances in Applications of Name Reactions in Multicomponent Reactions

Autor Majid M. Heravi, Vahideh Zadsirjan
en Limba Engleză Paperback – 31 mai 2020
Recent Advances in Applications of Name Reactions in Multicomponent Reactions is an ideal reference for researchers and postgraduate students studying organic chemistry, as well as synthetic organic chemists working on the development of novel methodologies for the synthesis of various heterocyclic systems, especially drug design and discovery, in both academia and industry. The book reviews recent applications of name reactions in multicomponents for the synthesis of heterocycles and examines recent advances in applications of significant name reactions, such as Ugi and Passirini, Click, Knoevenagel, Michael, Diels-Alder, Aldol, Mannich, Heck, Huisgen, and Suzuki in MCRs.
These reactions can be used in the synthesis of a wide variety of novel heterocycles with different sizes and heteroatoms, as well as in the total synthesis of natural products in order to decrease the number of synthetic steps. Since chiral inductions are necessary for most of these sequential name reactions, their asymmetric catalyzed reactions are also described.


  • Includes the synthesis of many heterocycles, which is ideal for synthetic organic chemists engaged in the synthesis of heterocyclic systems
  • Covers the recent advances of asymmetric synthesis of a wide range of heterocycles in satisfactory enantioselectivities (ees) or distereoselectivities (des)
  • Reviews the synthesis of a wide variety of interesting heterocycles by using a combination of different and versatile name reactions via MCRs
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Specificații

ISBN-13: 9780128185841
ISBN-10: 0128185848
Pagini: 438
Ilustrații: Approx. 150 illustrations
Dimensiuni: 216 x 276 mm
Greutate: 1 kg
Editura: ELSEVIER SCIENCE

Public țintă

Researchers, graduate and post-graduate students studying synthetic organic chemistry, specifically those involved in the development of new/novel methodologies for the synthesis of various heterocyclic systems. It is especially useful for those groups working in drug design and drug discovery

Cuprins

1. Introduction
2. Applications of name reactions in Multicomponent reactions2.1. Advances in Ugi reaction in MCRs2.2. Advances in Passerini reaction in MCRS2.3. Advances in Click reaction in MCRS2.4. Advances in Knoevenagel reaction in MCRS2.5. Advances in Michael reaction in MCRS2.6. Advances in Aldol reaction in MCRS2.7. Advances in Mannich reaction in MCRS2.8. Advances in Diels-Alder reaction in MCRS2.9. Advances in Heck reaction in MCRS2.10. Advances in Huisgen reaction in MCRS2.11. Advances in Suzuki reaction in MCRS
3. Multicomponent reaction via combinations of name reactions3.1. Knoevenagel Reaction/Michael reaction3.2. Knoevenagel Reaction/Diels-Alder reaction3.3. Michael Addition/Aldol reaction3.4. Michael Addition/Mannich reaction3.5. Ugi reaction/Heck reaction3.6. Ugi Reaction/Deils-Alder reaction3.7. Ugi Reaction/Huisgen reaction3.8. Ugi Reaction/Aldol reaction3.9. Heck Reaction/Suzuki reaction Conclusion References