In recent years, there has been a blossoming use of advanced technologies across a wide range of applications in the general area of health care and clinical practice; one such genre is the use of virtual reality technologies for the rehabilitation and support of people with disabilities. This development has been driven by a combination of factors related to increasing clinical need, technological advancements, and developing communities of excellence in the virtual rehabilitation field. In this book, we demonstrate recent advances that have been made across the past two decades of technological development in the area of virtual rehabilitation. The editors highlight the importance of a multidisciplinary and holistic approach to developing virtual rehabilitation systems that meet the needs of patients, therapists and other care givers.