Redox Chemistry and Biology of Thiols
Editat de Beatriz Alvarez, Marcelo Comini, Gustavo Salinas, Madia Trujilloen Limba Engleză Paperback – 25 mai 2022
- Runs from basic thiol biology and chemistry to applications and clinical translation
- Provides methods and protocols that will power new research across biomedicine, cell biology, plant biology, drug development, and protein folding and modulation
- Includes chapter contributions from international leaders in the field
Preț: 803.48 lei
Preț vechi: 1040.34 lei
-23% Nou
Puncte Express: 1205
Preț estimativ în valută:
153.76€ • 159.56$ • 128.52£
153.76€ • 159.56$ • 128.52£
Carte tipărită la comandă
Livrare economică 10-24 martie
Preluare comenzi: 021 569.72.76
Specificații
ISBN-13: 9780323902199
ISBN-10: 0323902197
Pagini: 746
Ilustrații: 250 illustrations (150 in full color)
Dimensiuni: 191 x 235 x 41 mm
Greutate: 1.47 kg
Editura: ELSEVIER SCIENCE
ISBN-10: 0323902197
Pagini: 746
Ilustrații: 250 illustrations (150 in full color)
Dimensiuni: 191 x 235 x 41 mm
Greutate: 1.47 kg
Editura: ELSEVIER SCIENCE
Public țintă
Life science researchers in biochemistry, molecular biology, and cell biology; clinical chemists and pharmaceutical scientists; and medical and analytical chemists Clinicians and studentsCuprins
1. Basic concepts of thiol chemistry and biology
2. Chemical basis of cysteine reactivity: Acidity and nucleophilicity
3. Computational functional analysis of cysteine residues in proteins
4. Global approaches for protein thiol redox state detection and quantification
5. Thiol oxidation by biologically-relevant reactive species
6. Thiyl radicals: formation, properties and detection
7. Detection of the oxidation products of thiols: disulfides, sulfenic, sulfinic and sulfonic acids
8. Biochemistry and detection of S-nitrosothiols
9. Thiol modification and signaling by biological electrophiles
10. Thioredoxin and glutathione reductases
11. Functional plasticity in the thioredoxin family: FeS-thio- and glutaredoxins
12. Glutathione and glutathione-dependent enzymes
13. Thiol and selenol-based peroxidases: Structure and catalytic properties
14. Thiol peroxidase-based redox relays
15. Compartmentalized disulphide bond formation pathways
16. Disulfide bond formation in Escherichia coli
17. Thiol-based redox probes
18. Selenocysteine-containing proteins
19. Overview of cysteine metabolism
20. Hydrogen sulfide and persulfides
21. The role of thiols in iron-sulfur cluster biogenesis
22. Thiol-based redox control in chloroplasts
23. Sugar-based cysteine thiols recruited for oxidative stress defence and redox regulation
24. Polyamine-based thiols in pathogens
25. Thiols in blood
26. A thiol chemistry perspective on redox medicine
27. Therapeutic applications of low-molecular-weight thiols and selenocompounds
28. Thiol targets in drug development to combat bacterial infections
2. Chemical basis of cysteine reactivity: Acidity and nucleophilicity
3. Computational functional analysis of cysteine residues in proteins
4. Global approaches for protein thiol redox state detection and quantification
5. Thiol oxidation by biologically-relevant reactive species
6. Thiyl radicals: formation, properties and detection
7. Detection of the oxidation products of thiols: disulfides, sulfenic, sulfinic and sulfonic acids
8. Biochemistry and detection of S-nitrosothiols
9. Thiol modification and signaling by biological electrophiles
10. Thioredoxin and glutathione reductases
11. Functional plasticity in the thioredoxin family: FeS-thio- and glutaredoxins
12. Glutathione and glutathione-dependent enzymes
13. Thiol and selenol-based peroxidases: Structure and catalytic properties
14. Thiol peroxidase-based redox relays
15. Compartmentalized disulphide bond formation pathways
16. Disulfide bond formation in Escherichia coli
17. Thiol-based redox probes
18. Selenocysteine-containing proteins
19. Overview of cysteine metabolism
20. Hydrogen sulfide and persulfides
21. The role of thiols in iron-sulfur cluster biogenesis
22. Thiol-based redox control in chloroplasts
23. Sugar-based cysteine thiols recruited for oxidative stress defence and redox regulation
24. Polyamine-based thiols in pathogens
25. Thiols in blood
26. A thiol chemistry perspective on redox medicine
27. Therapeutic applications of low-molecular-weight thiols and selenocompounds
28. Thiol targets in drug development to combat bacterial infections