In the realm of neurodegeneration, the intricate balance between life and death within cells is a subject of profound importance and intrigue. Regulated Cell Death (RCD) has become a key focus of research, shedding light on its complex mechanisms and implications for various neurodegenerative disorders.
Regulated Cell Death in Neurodegenerative Disorders explores the discovery, features, and implications of RCD in the context of neurodegenerative diseases. Each chapter delves into different RCD mechanisms, such as apoptosis, necroptosis, ferroptosis, pyroptosis, and autophagy-mediated cell death, providing unique insights into cellular demise in different neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, Multiple sclerosis, Amyotrophic lateral sclerosis, and Huntington’s disease.
Regulated Cell Death in Neurodegenerative Disorders features 14 chapters written by renowned experts in this field. Explore the complex world of RCD, covering its origins, mechanisms, and impact on neurodegenerative diseases, providing valuable insights into treatment options and therapeutic targets. Discover the diverse aspects of RCD modalities, the importance of chaperones, kinases, growth factors, inflammaging, mitochondrial dynamics, oxidative stress, and targeted strategies to prevent cell death in neurodegenerative disorders. This book covers molecular, cellular, and pharmacological mechanisms in all chapters from an applied science perspective.
This book not only shares knowledge but also offers hope by presenting therapeutic strategies to modulate RCD for combating neurodegenerative diseases. It reflects the ongoing pursuit of understanding, innovative treatments, and unraveling the mysteries surrounding cellular death in neurodegenerative contexts.

• Provides a comprehensive overview of different types of RCD
• Dissects the crosstalk between different types of RCD
• Explores the relevance of RCD mechanisms to neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease, Multiple sclerosis, Amyotrophic lateral sclerosis, and Huntington’s disease
• Examines several forms of regulated cell death, including apoptosis, necroptosis, ferroptosis, pyroptosis, and autophagy-mediated cell death
• Discusses the effect of Inflammaging and oxidative stress on different types of RCD
• Delves into the effect of chaperones, kinases, and growth factors on different RCD machinery
• Discusses the potential of targeted therapies aimed at interdicting cell death machineries
• Explores disease-modifying agents targeting RCD in neurodegenerative disorders