Cantitate/Preț
Produs

Relaxin and the Fine Structure of Proteins

Autor Christian Schwabe, Erika E. Büllesbach
en Limba Engleză Paperback – 6 ian 2013
Relaxin, perhaps more than any other hormone, has a varied history of eliciting enthusiasm, rejection, skepticism, and long lapses of neglect. Long after its discovery, it was a hormone in search of a physiological role in humans. Today, relaxin is implicated in mammary growth, development and function, ionotropic and chronotropic action on the heart, and angiogenic activity in both the peripheral tissues and the endometrium. It is best known for its effect on the uterus and the symphysis pubis in preparation for parturition. However, the literature suggests that not all functions occur in one species. This book describes how to obtain the necessary molecules or derivatives for research, reaching right into the design of new molecules for specific applications.
Citește tot Restrânge

Preț: 36911 lei

Nou

Puncte Express: 554

Preț estimativ în valută:
7064 7452$ 5904£

Carte tipărită la comandă

Livrare economică 01-15 ianuarie 25

Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9783662129111
ISBN-10: 3662129116
Pagini: 216
Ilustrații: XI, 200 p. 112 illus., 21 illus. in color.
Dimensiuni: 155 x 235 x 11 mm
Greutate: 0.31 kg
Ediția:Softcover reprint of the original 1st ed. 1998
Editura: Springer Berlin, Heidelberg
Colecția Springer
Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

1. Introduction.- 2. A Very Brief History.- 3. The Relaxin Insulin-Like Motif in Protein Structures.- 4. Other Mammalian and Chondrichtian Relaxins.- 5. Isolation and Sequence Analysis of Porcine Relaxin.- 6. The Initial Approach to Receptor-Binding Site Studies.- 7. The N-Terminal Region of the Relaxin A Chain.- 8. The Total Synthesis of Human Relaxin.- 9. Analytic of the Prototype.- 10. The Receptor-Binding Site of Relaxin.- 11. Merely a G (Glycine).- 12. The Development of Insulaxin, The First True “Zwitterhormon”.- 13. A Surprising Message from Murines.- 14. The Mouse, a Very Small Rat, a Very Big Mistake.- 15. Retro-D-Relaxin.- 16. The Relaxin-Like Factor.- 17. The Relaxin Receptor.- 18. Relaxin as a Drug.- 19. Relaxin and Genealogy.- Color Figures.

Caracteristici

A comprehensive discussion of the principles of protein topology in relation to biological function