V sovremennom mire chrezvychayno rasprostranena takaya khronicheskaya obstruktivnaya patologiya legkikh, kak bronkhial'naya astma i khronicheskaya obstruktivnaya bolezn' legkikh. Eti zabolevaniya mogut privodit' k stoykoy potere trudosposobnosti v svyazi s razvitiem legochno-serdechnoy nedostatochnosti. Tesnaya anatomicheskaya i funktsional'naya vzaimosvyaz' sistem krovoobrashcheniya i dykhaniya obuslavlivayut narushenie funktsional'nogo sostoyaniya odnoy iz nikh uzhe na samykh rannikh stadiyakh porazheniya drugoy. Takim obrazom, bol'shoe znachenie priobretayut neinvazivnye metody diagnostiki pozvolyayushchie otsenit' funktsional'nuyu aktivnost' sistemy regulyatsii sosudistogo tonusa, i tem samym sposobstvuyushchie prognozirovaniyu oslozhneniy so storony serdechno-sosudistoy sistemy. Tsel'yu nastoyashchego issledovaniya yavlyaetsya opredelenie osobennostey vazoreguliruyushchey funktsii endoteliya i ee vzaimosvyaz' s funktsional'nym sostoyaniem legochno-serdechnoy gemodinamiki, strukturoy i funktsiey pravykh otdelov serdtsa pri srednetyazhelom techenii KhOBL i BA.