This monograph is another in the series of studies on aspects of Russian defense and foreign policy being published by the Strategic Studies Institute (SSI). These monographs derive from a conference that was jointly sponsored by the Strategic Studies Institute; the Ellison Center for Russian, East European, and Central Asian Studies at the Jackson School of International Studies at the University of Washington; the Pacific Northwest National Laboratory's Pacific Northwest Center for Global Studies; and the Institute for Global and Regional Security Studies. This conference, titled "The U.S. and Russia: Regional Security Issues and Interests," was held in Washington, DC, on April 24-26, 2006, and examined many different regional dimensions of this bilateral relationship.