This book discusses the concept of stress based on accumulated scientific evidence so that the physiology and biochemistry of the stress response cycle can be better understood. General theories of stress are reviewed and discussed within a framework emphasizing physiology and biochemistry. The uniqueness of this book lies in its presentation of stress by illustrating anatomical pathways and physiological measurements as well as by discussing the establishment of links between memory, cognitive appraisal, coping and perception. New concepts relating to stress, including psychoneuroimmunology, social psychology and stress hormones such as galanin, are also discussed. Unique, too, is the discussion of stress-related metabolic derangements leading to hypertension, type 2 diabetes mellitus, dyslipidaemia, cancer, psychosis, as well as imbalances in body pH and electrolyte levels. This book is recommended for use by undergraduates, postgraduates, and researchers and practitioners in the medical, psychological and allied health fields.