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Self Eroding Matrix System

Autor Vivek Dave, Sarita Karole, Jitendra Bajaj
en Limba Engleză Paperback – 31 mar 2011
The aim of this study was to develop a lipid based formulation for a poorly soluble drug belonging to BCS Class II. The intention of the formulation design was to develop a "self eroding matrix system" made of lipidic excipients which would release the drug mainly by the mechanism of erosion. To attain such as system, lipidic excipients like stearic acid and hydrogenated castor oil were used as matrix formers and surfactants like sodium lauryl sulphate and gelucire 44/14 were used as matrix modifiers. The formulations prepared were subjected to physicochemical and in vitro dissolution and erosion studies.
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Specificații

ISBN-13: 9783639348088
ISBN-10: 3639348087
Pagini: 120
Dimensiuni: 150 x 220 x 7 mm
Greutate: 0.19 kg
Editura: VDM Verlag Dr. Müller e.K.

Notă biografică

Hello everyone, this is Vivek Dave from India. I have done Masters in Pharmaceutics from manipal college of pharmaceutical sciences, India in 2008. Since then I am involved in basic research of drug delivery of various drugs through transdermal and ocular route. I want to share my research experience through my this work.