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Self-organizing Neural Maps: The Retinotectal Map and Mechanisms of Neural Development: From Retina to Tectum

Autor John T. Schmidt
en Limba Engleză Paperback – 14 oct 2019
Self-organizing Neural Maps: From Retina to Tectum describes the underlying processes that determine how retinal fibers self-organize into an orderly visual map. The formation of neural maps is a fundamental organizing concept in neurodevelopment that can shed light on developmental mechanisms and the functions of genes elsewhere. The book presents a summary of research in the retinotectal field with an ultimate goal of synthesizing how underlying mechanisms in neural development harmoniously come together to create life. A broad spectrum of neuroscientists and biomedical scientists with differing backgrounds and varied expertise will find this book useful.


  • Describes the mechanisms relating to the developmental wiring of the retinotectal system
  • Brings together the state-of-the-art research in axon guidance and neuronal activity mechanisms in map formation
  • Focuses on topographical maps and inclusion of multiple animal models, from fish to mammals
  • Explores the molecular guidance and activity dependent cue components involved in neurodevelopment
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Specificații

ISBN-13: 9780128185797
ISBN-10: 0128185791
Pagini: 472
Dimensiuni: 152 x 229 mm
Greutate: 0.63 kg
Editura: ELSEVIER SCIENCE

Cuprins

1. Overview and Basics of the Retinotectal Projection2. Early Work Supports, but Also Contradicts, Rigid Chemoaffinity3. The search for chemoaffinity molecules - verification of molecular gradients4. Plasticity after surgical ablations shows the limits of chemoaffinity5. Natural Plasticity - Analysis of the effects of divergent retinal and tectal growth on the projection6. Specification and developmental genetics of Eph/ephrin gradients7. Growth of retinal axons along the visual pathway8. Genetic Analysis of the molecular gradients defining map formation9. Activity mechanisms shape central retinal projections10. Activity: Molecular signaling to growth mechanisms