Seroquel is used alone or in combination to treat Schizophrenia and Bipolar Effective Disorder and as an adjunct to help in the treatment of Major Depressive Illness. The drug is classified as an atypical antipsychotic and works by altering the levels of the neurotransmitters dopamine and serotonin while also acting as a adrenergic antagonists and a powerful antihistamine. For patients taking Seroquel, keeping a daily dosage journal is recommended as doing so can help patients keep track of their progress and increase medication adherence.