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Short Pulse Laser Systems for Biomedical Applications: SpringerBriefs in Applied Sciences and Technology

Autor Kunal Mitra, Stephanie Miller
en Limba Engleză Paperback – 23 mar 2017
This book presents practical information on the clinical applications of short pulse laser systems and the techniques for optimizing these applications in a manner that will be relevant to a broad audience, including engineering and medical students as well as researchers, clinicians, and technicians. Short pulse laser systems are useful for both subsurface tissue imaging and laser induced thermal therapy (LITT), which hold great promise in cancer diagnostics and treatment. Such laser systems may be used alone or in combination with optically active nanoparticles specifically administered to the tissues of interest for enhanced contrast in imaging and precise heating during LITT. Mathematical and computational models of short pulse laser-tissue interactions that consider the transient radiative transport equation coupled with a bio-heat equation considering the initial transients of laser heating were developed to analyze the laser-tissue interaction during imaging and therapy. Experiments were first performed to characterize the tissue optical properties needed to optimize the dose for thermal therapy. Experiments were then performed on animal models to characterize the heat affected zone for LITT. The experimental measurements were also validated using the computational models. 

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Specificații

ISBN-13: 9783319542522
ISBN-10: 3319542524
Pagini: 52
Ilustrații: VII, 49 p. 26 illus., 9 illus. in color.
Dimensiuni: 155 x 235 x 3 mm
Greutate: 0.1 kg
Ediția:1st ed. 2017
Editura: Springer International Publishing
Colecția Springer
Seria SpringerBriefs in Applied Sciences and Technology

Locul publicării:Cham, Switzerland

Cuprins

Introduction.- Short Pulse Laser Imaging.- Short Pulse Laser Based Thermal Therapy.- Use of Nanoparticles to Optimize Short Pulse Laser Based Biomedical Applications.

Notă biografică

Kunal Mitra is Professor of Biomedical Engineering at Florida Institute of Technology. 

Stephanie Miller is a graduate student in the Department of Biomedical Engineering at Florida Institute of Technology.


Textul de pe ultima copertă

This book presents practical information on the clinical applications of short pulse laser systems and the techniques for optimizing these applications in a manner that will be relevant to a broad audience, including engineering and medical students as well as researchers, clinicians, and technicians. Short pulse laser systems are useful for both subsurface tissue imaging and laser induced thermal therapy (LITT), which hold great promise in cancer diagnostics and treatment. Such laser systems may be used alone or in combination with optically active nanoparticles specifically administered to the tissues of interest for enhanced contrast in imaging and precise heating during LITT. Mathematical and computational models of short pulse laser-tissue interactions that consider the transient radiative transport equation coupled with a bio-heat equation considering the initial transients of laser heating were developed to analyze the laser-tissue interaction during imaging and therapy. Experiments were first performed to characterize the tissue optical properties needed to optimize the dose for thermal therapy. Experiments were then performed on animal models to characterize the heat affected zone for LITT. The experimental measurements were also validated using the computational models. 

Caracteristici

Analyzes several clinically relevant uses of short pulse laser systems, including the newest ones used in cancer diagnostics and treatment Concisely presents key points regarding the results of lab experiments and computer simulations in order to demonstrate the fundamental science behind the applications of this technology Demonstrates how to improve the safety and efficacy of this technology through enhanced contrast in imaging and precise heating