Dana Knowles is the only female federal agent working as an elite nuclear weapons courier for the Department of Energy at Y-12 in Oak Ridge, Tennessee: the "Secret City" of WWII where uranium was enriched to create the first atomic bomb. Dana has become frustrated that her training and skills will never be put to the test, but she is unaware that she has provoked a psychotic killer to seize a nuclear weapon that threatens the lives of millions of innocent citizens. Only Dana can unravel the identity of the madman and stop him as time ticks down to "Six Minutes to Midnight" the setting of the symbolic Doomsday Clock that measures how close we are to nuclear disaster.