In Ethiopian context, most of the studies on classroom interaction attempted to investigate the interaction pattern using the vast known Flanders's Interaction Analysis. These studies focused on investigating the freedom and control of the teacher on the learners. However, it is this explanatory qualitative case study which attempted to investigate the nature of mathematics classroom interaction in city Secondary School, Addis Ababa, Ethiopia. It took the existing mathematics classroom social norms to understand the nature of interaction in to consideration. It aimed to find out and examine factors that could influence teacher-student and student-student interaction from the social constructivists and symbolic interactionists perspectives. This study focused on the nature of interactions that occurred during regular mathematics classroom activities. The study offers empirical and theoretical reflections on the nature of classroom interaction.