Standardizing Pharmacology: Assays and Hormones: Discoveries in Pharmacology, Volume 2
Editat de Michael J. Parnham, Clive Page, Jacques Bruinvelsen Limba Engleză Hardback – 2 mar 2023
Sections cover key discoveries in receptor theory, pharmacological methods and the development of hormone therapy, including J. Parascandola on the development of receptor theory, R.S. Yalow on radioimmunoassay, M. van Rossum and J.T L.A. Hurkmans on bioassays, M. Tausk on androgen therapy and C. Djerassi on oral contraceptives, with commentaries from experts such as T. Hökfelt and V.C. Jordan.
- Contains primary-source documents currently unavailable elsewhere
- Presents the science behind major pharmacological breakthroughs by those who discovered them
- Includes commentary contextualizing the importance of discoveries and related readings
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Specificații
ISBN-13: 9780323855174
ISBN-10: 0323855172
Pagini: 284
Dimensiuni: 191 x 235 x 18 mm
Greutate: 0.7 kg
Ediția:2
Editura: ELSEVIER SCIENCE
ISBN-10: 0323855172
Pagini: 284
Dimensiuni: 191 x 235 x 18 mm
Greutate: 0.7 kg
Ediția:2
Editura: ELSEVIER SCIENCE
Public țintă
Primary: Academic researchers in pharmacology and medicine as well as advanced students in the area and teachers needing supplementary course material for undergraduate and graduate pharmacology or medical courses.Secondary: It may also be of interest to those who study the history of medicine.
Cuprins
Section I. Redirected traffic: the history of drugs affecting haemodynamics
1. The control of blood pressure
Part 1 - The discovery of beta adrenoceptor blocking drugs
Part 2 - Peripheral anti-hypertensives: ganglion and adrenergic neurone-blocking agents
Section II. The discovery and application of hormones
2. The emergence of endocrinology
3. Sex hormones
Part 1 - Androgens and anabolic steroids
Part 2 - The biological history of the Pill
Part 3 - The chemical history of the Pill
Section III. Overcoming the body's defence system
4. Anti-inflammatory drugs
Part 1 - The proliferation of non-steroidal anti-inflammatory drugs (NSATDS)
Part 2 - The story of aspirin, H.O.J. Collier
5. The inhibition of allergic reactions
Part I - Histamine receptor antagonists
Part 2 - Asthma: a long and continuing story
Section IV. Assays and the molecular basis of drug action
6. A probe for the fine structures of the body
7. Isolated smooth muscle in pharmacology
Part 1 - The guts of the matter: contribution of studies on smooth muscle to discoveries in pharmacology
Part 2 - Bioassay: a pharmacological endeavour
8. Making visible the invisible (Recollections of the first experiences with the histochemical fluorescence method for visualization of tissue monoamines)
9. Receptors in pharmacology
Section V. History of chemotherapy
10. From dyes to drugs
11. The discovery of penicillin and cephalosporins
12. The antibiotic explosion
1. The control of blood pressure
Part 1 - The discovery of beta adrenoceptor blocking drugs
Part 2 - Peripheral anti-hypertensives: ganglion and adrenergic neurone-blocking agents
Section II. The discovery and application of hormones
2. The emergence of endocrinology
3. Sex hormones
Part 1 - Androgens and anabolic steroids
Part 2 - The biological history of the Pill
Part 3 - The chemical history of the Pill
Section III. Overcoming the body's defence system
4. Anti-inflammatory drugs
Part 1 - The proliferation of non-steroidal anti-inflammatory drugs (NSATDS)
Part 2 - The story of aspirin, H.O.J. Collier
5. The inhibition of allergic reactions
Part I - Histamine receptor antagonists
Part 2 - Asthma: a long and continuing story
Section IV. Assays and the molecular basis of drug action
6. A probe for the fine structures of the body
7. Isolated smooth muscle in pharmacology
Part 1 - The guts of the matter: contribution of studies on smooth muscle to discoveries in pharmacology
Part 2 - Bioassay: a pharmacological endeavour
8. Making visible the invisible (Recollections of the first experiences with the histochemical fluorescence method for visualization of tissue monoamines)
9. Receptors in pharmacology
Section V. History of chemotherapy
10. From dyes to drugs
11. The discovery of penicillin and cephalosporins
12. The antibiotic explosion