There are thousands of college, university, and private modern observatories worldwide, equipped with state-of-the-art high tech equipment that only two decades ago was available to the world's largest research facilities. For the advanced amateur, and the university astronomy class, there are research projects available in which the non-professional not only can contribute real science to the body of knowledge, but provide true opportunities of discovery throughout the cosmos. In this Supernova Study Guide, the author presents the foundation for one of the most exciting and rewarding of all research quests: the search for stellar explosions in other galaxies - the Supernovae, one of nature's most rare events. This represents the first such Guide in which the author provides 300 empirically-determined galaxy targets for supernova searches and combines this vital list with the tools and techniques, step-by-step instructions, for successful supernova searches and research.