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Systems Biology and In-Depth Applications for Unlocking Diseases: Principles, Tools, and Application to Disease

Editat de Babak Sokouti
en Limba Engleză Paperback – 8 noi 2024
Systems Biology and In-Depth Applications for Unlocking Diseases provides the essence of systems biology approaches in a practical manner illustrating the basic principles essential to develop and model in real life science applications. Methodologies covered show how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment. Systematically written in 4 parts, this book first provides an introduction and history of systems biology; second, it provides the tools and resources needed for the structure and function of biological systems; next, it provides the evidence of systems biology in action to better understand disease connections; and finally, it provides the extensions of systems biology in various scientific fields including pharmacology, immunology, vaccinology, neuroscience, virology, and medicine. Examples include big data techniques, scale networks, mathematical model development, and much more. This is the perfect reference to provide the fundamental base of knowledge needed for systems biologists, professionals in systems medicine, computational biologists, and bioinformaticians, whether needed for immediate application or for building a comprehensive understanding of the field.


  • Provides detailed and comprehensive coverage of the field of systems biology
  • Delivers instruction on how to interrogate biological data, with the purpose of obtaining insight about disease diagnosis, prognosis, and treatment
  • Makes effective steps towards personalized medicine in the treatment of disease
  • Explains effective disease treatment strategies at early diagnosis stages
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Specificații

ISBN-13: 9780443223266
ISBN-10: 0443223262
Pagini: 354
Dimensiuni: 216 x 276 mm
Greutate: 0.45 kg
Editura: ELSEVIER SCIENCE

Cuprins

  1. Systems biology at a glance
  2. Brief information on cellular biology and signaling pathways
  3. The multiscale causality nature of human cancer: A systemic approach
  4. From sketch to landscape: Transforming neuronal concepts across technological change
  5. Challenges in evolutionary computing in the context of integrated bioinformatics
  6. Kinetics and dynamics of biological systems
  7. Biological data sources for advancement in system biology
  8. High-throughput data analysis in systems biology: Techniques, challenges and applications in modern scientific research
  9. High throughput data: Single-nucleotide polymorphisms in depth
  10. The significance and evolution of biological databases in systems biology
  11. Programming, tools, and software
  12. Big data analysis techniques
  13. Reconstruction of genomic and proteomic scale network structures and functions
  14. Validation strategies in systems biology research
  15. Systems in pharmacology – principles, methods, and applications
  16. Systems immunology
  17. Systems virology
  18. Systems vaccinology
  19. Systems neuroscience
  20. Implications of systems in biology understanding the pathophysiology of neurological diseases
  21. Systems medicine
  22. From systems thinking to P4 medicine
  23. Systems biology of cancer
  24. Repurposing, effects, design, and discovery of drugs in systems biology
  25. Future directions on systems biology