Targeting of Drugs 2: Optimization Strategies: NATO Science Series A:, cartea 199

Biological Dispersion and the Design of Site-Specific Protein Therapeutic Systems.- Recombinant Ligand-Toxin Conjugates, Domain Engineering and the Search for Targeted Pharmaceuticals.- Extravascular Diffusion and Convection of Antibodies in Tumors.- Antitumor Effects of Six Ricin A-Chain Immunotoxins of Potential Use in the Treatment of Hodgkin’s Disease.- Enhancement of Hormone Activity by Monoclonal Antibodies.- Modeling of Cell Membrane Targeting: Specific Recognition, Binding and Protein Domain Formation in Ligand- Containing Model Biomembranes.- Endocytosis of Cell Surface Molecules and Intracellular Delivery of Materials Encapsulated in Targeted Liposomes.- Tissue Specific Serum Opsonins and Phagocytosis of Liposomes.- Liposome Targeting to Tumor Cells In Vivo.- Stabilization of Lipid Microstructures: Fundamentals and Applications.- Non-Ionic Surfactant Vesicles as Carriers of Doxorubicin.- Targeted Therapy of Liver Carcinoma.- Drug Delivery Systems: The Industrial View.- Controlled Delivery to the Brain.- Polymeric Delivery Systems.- Participants Photograph.- Contributors.