Targeting the IL-17 Pathway in Inflammatory Disorders
Autor Cong-Qiu Chuen Limba Engleză Paperback – 27 dec 2016
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Specificații
ISBN-13: 9783319280394
ISBN-10: 3319280392
Pagini: 80
Ilustrații: XV, 102 p. 6 illus. in color.
Dimensiuni: 127 x 203 x 7 mm
Greutate: 0.17 kg
Ediția:1st ed. 2017
Editura: Springer International Publishing
Colecția Adis
Locul publicării:Cham, Switzerland
ISBN-10: 3319280392
Pagini: 80
Ilustrații: XV, 102 p. 6 illus. in color.
Dimensiuni: 127 x 203 x 7 mm
Greutate: 0.17 kg
Ediția:1st ed. 2017
Editura: Springer International Publishing
Colecția Adis
Locul publicării:Cham, Switzerland
Public țintă
Professional/practitionerCuprins
Introduction.- Overview of IL-17 family.-Il-17 in host defense.- Th17 cells: differentiation and regulation.- The role of the IL-17/Th17 pathway in the pathogenesis of autoimmune inflammatory diseases.- Therapeutic applications: strategies and molecules targeting the IL-17/Th17 pathway.- Concluding remarks
Notă biografică
Cong-Qiu Chu, MD, PhD is associate professor of medicine at Oregon Health & Science University and VA Portland Health Care System, Portland, Oregon. Dr Chu obtained his MD from Normal Bethune University of Medical Sciences, Changchun, China and PhD from the Kennedy Institute of Rheumatology, University of London, London, UK; completed his internal medicine residency at Peking Union Medical College Hospital, Beijing and Wayne State University Detroit Medical Center, Detroit, Michigan and rheumatology fellowship at University of Washington, Seattle. Dr Chu has a career long interest in the pathogenesis of rheumatoid arthritis (RA). His seminal observation that tumor necrosis factor (TNF) is over-expressed in RA joint tissue helped the development of TNF inhibitors for therapy of RA. His contribution was recognized by European League Against Rheumatism Young Investigator Award in 1991. Dr Chu is one of the investigators who first demonstrated that T helper type 1 (Th1) cells are not the cell types mediating autoimmune inflammatory diseases, which were later uncovered to be mediated by Th17 cells. Dr Chu’s current research includes developing novel therapeutic strategies using RNA interference technology for precise targeting Th17 cells for inflammatory diseases and developing optimal management strategies for early RA.
Caracteristici
A comprehensive overview of the role of IL-17/Th17 in inflammatory disorders and discussion of the latest therapeutic advances targeting this pathway
Includes the latest evidence-based treatment recommendations based on the most up-to-date research and clinical trial data
A wide range of engaging images, tables, and diagrams illustrate the concepts discussed in the book
Written by a renowned international expert on IL-17 research in the clinical setting
Includes the latest evidence-based treatment recommendations based on the most up-to-date research and clinical trial data
A wide range of engaging images, tables, and diagrams illustrate the concepts discussed in the book
Written by a renowned international expert on IL-17 research in the clinical setting