When it comes to working and learning, collaboration is often the key to success. In a team, tasks can be completed more efficiently, complex issues are easier to grasp and, as we all know, learning is not only an individual but also a social process. The articles in this collection illustrate a variety of opportunities and challenges that the use of virtual spaces and virtual technologies presents for successful teamwork. The collections' aim is to contribute to exploratory research as well as pilot studies of concepts and methods in the use of virtuality, with contributions from different professional and application perspectives. The question of whether teamwork will increasingly take place in virtual space in the future is clearly answered in the affirmative. For this reason, it is necessary to continue to investigate the organisation of virtual collaboration in the future and to continuously develop new concepts for collaboration. This publication is a snapshot of these ongoing developments. It is intended to inspire practitioners to innovate in the design of collaboration in work and learning environments and to stimulate researchers in their future experiments and research approaches.