Telomeres: Biomarkers of a Healthy Life and Successful Aging
Editat de Aristidis Tsatsakis, Paraskevi Kallinteri, Elisavet Renierien Limba Engleză Hardback – 5 feb 2025
Preț: 1530.36 lei
Preț vechi: 2054.76 lei
-26% Nou
Puncte Express: 2296
Preț estimativ în valută:
292.88€ • 304.23$ • 243.28£
292.88€ • 304.23$ • 243.28£
Carte nepublicată încă
Doresc să fiu notificat când acest titlu va fi disponibil:
Se trimite...
Preluare comenzi: 021 569.72.76
Specificații
ISBN-13: 9789815129496
ISBN-10: 981512949X
Pagini: 764
Ilustrații: 88
Dimensiuni: 152 x 229 mm
Ediția:1
Editura: Jenny Stanford Publishing
Colecția Jenny Stanford Publishing
ISBN-10: 981512949X
Pagini: 764
Ilustrații: 88
Dimensiuni: 152 x 229 mm
Ediția:1
Editura: Jenny Stanford Publishing
Colecția Jenny Stanford Publishing
Public țintă
Academic and PostgraduateCuprins
PART I AGING
1 Aging
Nikolaos Panagiotou
PART II TELOMERE LENGTH
2 Telomere Length as a Marker of Biological Age
Stella Baliou, Persefoni Fragkiadaki, Elena Vakonaki, Petros Ioannou, Elisavet Renieri, Manolis Tzatzarakis, and Aristidis Tsatsakis
3 Computational Tools for Telomere Length Measurement
Irene Fragkiadoulaki, Athanasios Alegkakis, Elisavet Renieri, and Aristidis Tsatsakis
PART III LIFESTYLE
4 The Impact of the First 1000 Days of Human Life on Telomere Length
Maria Theodora Vitiadou, Nicolina Anagnostatou, Elena Vakonaki, Aristidis Tsatsakis, and Eleftheria Hatzidaki
5 Diet as a Strategy to Lengthen Life Expectancy
Konstantinos Xenos and Evgenia Alexandrou
6 The First Steps toward Balanced Eating
Evangelos Zoumpaneas
7 Fasting and Telomeres
Antonis Tsintarakis, Michael Stroumpakis, Maria Sifaki, Dimitra Nikolopoulou, Vassilis Zoumpourlis, and Aristidis Tsatsakis
8 The Impact of Exercise on Telomere Length
Stella Baliou, Petros Ioannou, Vassilis Zoumpourlis, Demetrios Spandidos, and Aristidis Tsatsakis
9 Telomere Shortening: A Link between Substances of Abuse and Accelerated Senescence
Lina Solange Matos, João Pedro Silva, and Félix Carvalho
10 Telomere Length as Potential Metal Exposure Biomarker: State of the Art and Perspectives
Anatoly Skalny, Michael Aschner, Aristidis Tsatsakis, Petr Litvitsky, Andrey Svistunov, Monica Paoliello, Abel Santamaria, Ji-Chang Zhou, and Alexey Tinkov
PART IV DISEASES
11 Telomere’s Association with Diseases
Eleni Ntoumou
12 Telomere Length and Metabolomics in Autoimmune Diseases
Dimitris Tsoukalas, Evangelia Sarandi, Symeon Xenidis, and Aristidis Tsatsakis
13 Osteoarthritis
Lydia-Nefeli Thrapsanioti, Aikaterini Berdiaki, Fotios Kakridonis, Aristidis Tsatsakis, and Dragana Nikitovic
14 Microbiome
George Pantazidis
15 Intestinal Microbiota and Human Telomere Length: A Dynamic Crosstalk between Two Worlds
Taxiarchis Konstantinos Nikolouzakis, Michael Koukakis, Aristidis Tsatsakis, and John Tsiaoussis
16 Cardiovascular Diseases and Telomeres
Sergey Savko, Christina Tsitsimpikou, Emmanouel Papadakis, Demetrios Spandidos, Aristidis Tsatsakis, and Konstantinos Tsarouhas
17 Decelerating Cardiovascular Aging: Diet, Exercise, and Medication
Konstantinos Tsarouhas, Christina Tsitsimpikou, and Emmanouel Papadakis
18 Male and Female Infertility
Elisavet Kouvidi, Elisavet Renieri, and Aristidis Tsatsakis
19 Telomere Length and Human Carcinogenesis: Liable or Random Finding?
Taxiarchis Konstantinos Nikolouzakis, Aristidis Tsatsakis, and John Tsiaoussis
20 Telomere Length Biology in Blood Disorders and Childhood
Cancer
Kleoniki Roka and Eftichia Stiakaki
21 Skin Aging
Maria Sifaki, Stella Baliou, Sabine Kruger-Krasagakis, Polytimi Sidiropoulou, Dimitra Nikolopoulou, and Aristidis Tsatsakis
PART V THERAPEUTIC APPROACHES
22 Telomeres, Telomerase, and Shelterin Complex: Promising Drug Targets for Longevity, Age-Related Diseases, and Cancer
Marios Spanakis and Aristidis Tsatsakis
23 Therapeutic Targeting of Telomerase
Eren Ozcagli, Esma Söylemez Yeşilçimen, Çiğdem Sevim, Mehtap Kara, and Aristidis Tsatsakis
1 Aging
Nikolaos Panagiotou
PART II TELOMERE LENGTH
2 Telomere Length as a Marker of Biological Age
Stella Baliou, Persefoni Fragkiadaki, Elena Vakonaki, Petros Ioannou, Elisavet Renieri, Manolis Tzatzarakis, and Aristidis Tsatsakis
3 Computational Tools for Telomere Length Measurement
Irene Fragkiadoulaki, Athanasios Alegkakis, Elisavet Renieri, and Aristidis Tsatsakis
PART III LIFESTYLE
4 The Impact of the First 1000 Days of Human Life on Telomere Length
Maria Theodora Vitiadou, Nicolina Anagnostatou, Elena Vakonaki, Aristidis Tsatsakis, and Eleftheria Hatzidaki
5 Diet as a Strategy to Lengthen Life Expectancy
Konstantinos Xenos and Evgenia Alexandrou
6 The First Steps toward Balanced Eating
Evangelos Zoumpaneas
7 Fasting and Telomeres
Antonis Tsintarakis, Michael Stroumpakis, Maria Sifaki, Dimitra Nikolopoulou, Vassilis Zoumpourlis, and Aristidis Tsatsakis
8 The Impact of Exercise on Telomere Length
Stella Baliou, Petros Ioannou, Vassilis Zoumpourlis, Demetrios Spandidos, and Aristidis Tsatsakis
9 Telomere Shortening: A Link between Substances of Abuse and Accelerated Senescence
Lina Solange Matos, João Pedro Silva, and Félix Carvalho
10 Telomere Length as Potential Metal Exposure Biomarker: State of the Art and Perspectives
Anatoly Skalny, Michael Aschner, Aristidis Tsatsakis, Petr Litvitsky, Andrey Svistunov, Monica Paoliello, Abel Santamaria, Ji-Chang Zhou, and Alexey Tinkov
PART IV DISEASES
11 Telomere’s Association with Diseases
Eleni Ntoumou
12 Telomere Length and Metabolomics in Autoimmune Diseases
Dimitris Tsoukalas, Evangelia Sarandi, Symeon Xenidis, and Aristidis Tsatsakis
13 Osteoarthritis
Lydia-Nefeli Thrapsanioti, Aikaterini Berdiaki, Fotios Kakridonis, Aristidis Tsatsakis, and Dragana Nikitovic
14 Microbiome
George Pantazidis
15 Intestinal Microbiota and Human Telomere Length: A Dynamic Crosstalk between Two Worlds
Taxiarchis Konstantinos Nikolouzakis, Michael Koukakis, Aristidis Tsatsakis, and John Tsiaoussis
16 Cardiovascular Diseases and Telomeres
Sergey Savko, Christina Tsitsimpikou, Emmanouel Papadakis, Demetrios Spandidos, Aristidis Tsatsakis, and Konstantinos Tsarouhas
17 Decelerating Cardiovascular Aging: Diet, Exercise, and Medication
Konstantinos Tsarouhas, Christina Tsitsimpikou, and Emmanouel Papadakis
18 Male and Female Infertility
Elisavet Kouvidi, Elisavet Renieri, and Aristidis Tsatsakis
19 Telomere Length and Human Carcinogenesis: Liable or Random Finding?
Taxiarchis Konstantinos Nikolouzakis, Aristidis Tsatsakis, and John Tsiaoussis
20 Telomere Length Biology in Blood Disorders and Childhood
Cancer
Kleoniki Roka and Eftichia Stiakaki
21 Skin Aging
Maria Sifaki, Stella Baliou, Sabine Kruger-Krasagakis, Polytimi Sidiropoulou, Dimitra Nikolopoulou, and Aristidis Tsatsakis
PART V THERAPEUTIC APPROACHES
22 Telomeres, Telomerase, and Shelterin Complex: Promising Drug Targets for Longevity, Age-Related Diseases, and Cancer
Marios Spanakis and Aristidis Tsatsakis
23 Therapeutic Targeting of Telomerase
Eren Ozcagli, Esma Söylemez Yeşilçimen, Çiğdem Sevim, Mehtap Kara, and Aristidis Tsatsakis
Recenzii
“This book unsparingly lays out the challenges of worldwide aging and its growing and possibly insurmountable health and economic challenges. A powerful boost to the credibility of the book is its rigorous examination of the validity of the methods of telomere impact assessment, which facilitates understanding of what has been determined of the impact of our lifestyles on our telomere processes and also the effects of some major disease states.”
Michael D. Coleman
Aston University, United Kingdom
“The book provides state-of-the-art information and deepens the understanding of telomere importance in healthy life and aging written by internationally recognized experts in their own field. It provides a timely update on the latest research outcomes and scientific breakthroughs in the field of telomeres, and it should be of interest to students, researchers, experts in various disciplines and the general reader.”
Michael Aschner
Albert Einstein College of Medicine, USA
“This text distinguishes itself with an extensive and insightful analysis that seamlessly connects fundamental biological understanding with the prospects of therapeutic intervention. By bridging the gap between basic science and clinical application, the book introduces a groundbreaking approach to exploring the potential of telomere science in enhancing health span and offers a holistic view of the current landscape of research and therapy development. Designed with a broad audience in mind, this book is an invaluable resource for a diverse range of readers, from researchers and clinicians deeply entrenched in the study of genetics and aging, to those with a keen interest in the broader implications of telomere science for preventive medicine.”
Thomas Hartung
Johns Hopkins Bloomberg School of Public Health, USA
“Prof. Tsatsakis’ book masterfully demystifies the role of telomeres in dictating the pace of our biological clock through a narrative that is not only scientifically rich but also deeply personal. Each chapter unfolds the intricate dance of telomere replication, a process pivotal to our understanding of aging and the potential onset of senescence.”
Ananya Nag
CEO, Aenaos Life
“The book provides state-of-the-art information and deepens understanding of the importance of telomere integrity in maintaining healthy life and aging. The book is written by internationally recognized experts in their fields and provides a timely update on the latest research outcomes and scientific breakthroughs in telomere biology and disease/aging linkage. The comprehensive nature of the book makes it an excellent reference in telomere biology in general and constitutes a must-read for not only students, researchers, and experts in aging but also those in other disciplines as well as the general reader.”
Prof. Michael Antoniou
King's College London, UK
Guy's Hospital, London, UK
“I highly recommend this book to anyone interested in understanding the complex relationship between our genetic blueprint and environment. This book offers a timely and critical exploration of telomeres and is sure to be of great value to all who seek to promote good health, longevity, and toxicants' role.”
Dr Mohammad Abdollahi
Tehran University of Medical Sciences
“Modern progressive scientific advancements have impacted all aspects of human life, even the most sacred such as birth and death. The discovery of telomeres has provided humanity with unprecedented opportunities to both predict and to control the life expectancy. The book systematizes and details all current knowledge on the aging mechanisms and solutions for their deceleration. These issues concern everyone. Therefore, this edition can be recommended to the widest range of readers.”
Prof. Victor A. Tutelyan
Full Member of the Russian Academy of Sciences and WHO Food Safety Expert
Michael D. Coleman
Aston University, United Kingdom
“The book provides state-of-the-art information and deepens the understanding of telomere importance in healthy life and aging written by internationally recognized experts in their own field. It provides a timely update on the latest research outcomes and scientific breakthroughs in the field of telomeres, and it should be of interest to students, researchers, experts in various disciplines and the general reader.”
Michael Aschner
Albert Einstein College of Medicine, USA
“This text distinguishes itself with an extensive and insightful analysis that seamlessly connects fundamental biological understanding with the prospects of therapeutic intervention. By bridging the gap between basic science and clinical application, the book introduces a groundbreaking approach to exploring the potential of telomere science in enhancing health span and offers a holistic view of the current landscape of research and therapy development. Designed with a broad audience in mind, this book is an invaluable resource for a diverse range of readers, from researchers and clinicians deeply entrenched in the study of genetics and aging, to those with a keen interest in the broader implications of telomere science for preventive medicine.”
Thomas Hartung
Johns Hopkins Bloomberg School of Public Health, USA
“Prof. Tsatsakis’ book masterfully demystifies the role of telomeres in dictating the pace of our biological clock through a narrative that is not only scientifically rich but also deeply personal. Each chapter unfolds the intricate dance of telomere replication, a process pivotal to our understanding of aging and the potential onset of senescence.”
Ananya Nag
CEO, Aenaos Life
“The book provides state-of-the-art information and deepens understanding of the importance of telomere integrity in maintaining healthy life and aging. The book is written by internationally recognized experts in their fields and provides a timely update on the latest research outcomes and scientific breakthroughs in telomere biology and disease/aging linkage. The comprehensive nature of the book makes it an excellent reference in telomere biology in general and constitutes a must-read for not only students, researchers, and experts in aging but also those in other disciplines as well as the general reader.”
Prof. Michael Antoniou
King's College London, UK
Guy's Hospital, London, UK
“I highly recommend this book to anyone interested in understanding the complex relationship between our genetic blueprint and environment. This book offers a timely and critical exploration of telomeres and is sure to be of great value to all who seek to promote good health, longevity, and toxicants' role.”
Dr Mohammad Abdollahi
Tehran University of Medical Sciences
“Modern progressive scientific advancements have impacted all aspects of human life, even the most sacred such as birth and death. The discovery of telomeres has provided humanity with unprecedented opportunities to both predict and to control the life expectancy. The book systematizes and details all current knowledge on the aging mechanisms and solutions for their deceleration. These issues concern everyone. Therefore, this edition can be recommended to the widest range of readers.”
Prof. Victor A. Tutelyan
Full Member of the Russian Academy of Sciences and WHO Food Safety Expert
Notă biografică
Aristidis Tsatsakis is the director of the Department of Toxicology and Forensic Sciences at the Medical School of the University of Crete and the University Hospital of Heraklion, Greece. He is the founder and chief scientific leader of the University of Crete spinoff company ToxPlus S.A. and the startup LifePlus. Prof. Tsatsakis’ motivation logo “Toxicology addresses society’s real-life risks for sustainable health and wellbeing” is indicated on the EUROTOX 2025 website.
Descriere
This book provides a comprehensive overview of aging and its mechanisms through the prism of telomere length and its link to lifestyle parameters and environmental pollutants, diseases where telomere length attrition is prominent, and therapeutic approaches to slow down or prevent the process of telomere length reduction.